ID Q67NT9_SYMTH Unreviewed; 214 AA.
AC Q67NT9;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000313|EMBL:BAD40654.1};
GN OrderedLocusNames=STH1669 {ECO:0000313|EMBL:BAD40654.1};
OS Symbiobacterium thermophilum (strain T / IAM 14863).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Symbiobacteriaceae;
OC Symbiobacterium.
OX NCBI_TaxID=292459 {ECO:0000313|EMBL:BAD40654.1, ECO:0000313|Proteomes:UP000000417};
RN [1] {ECO:0000313|EMBL:BAD40654.1, ECO:0000313|Proteomes:UP000000417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T / IAM 14863 {ECO:0000313|Proteomes:UP000000417};
RX PubMed=15383646; DOI=10.1093/nar/gkh830;
RA Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K.,
RA Ikeda H., Hattori M., Beppu T.;
RT "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium
RT that depends on microbial commensalism.";
RL Nucleic Acids Res. 32:4937-4944(2004).
CC -!- FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid
CC by incorporating acyl moiety at the 2 position.
CC {ECO:0000256|ARBA:ARBA00037183}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-
CC sn-glycero-3-phosphate + CoA; Xref=Rhea:RHEA:19709,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342,
CC ChEBI:CHEBI:58608; EC=2.3.1.51;
CC Evidence={ECO:0000256|ARBA:ARBA00001141};
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DR EMBL; AP006840; BAD40654.1; -; Genomic_DNA.
DR RefSeq; WP_011195798.1; NC_006177.1.
DR AlphaFoldDB; Q67NT9; -.
DR STRING; 292459.STH1669; -.
DR KEGG; sth:STH1669; -.
DR eggNOG; COG0204; Bacteria.
DR HOGENOM; CLU_027938_4_5_9; -.
DR OrthoDB; 9803035at2; -.
DR Proteomes; UP000000417; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd07989; LPLAT_AGPAT-like; 1.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10434; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR10434:SF60; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE LPAT1, CHLOROPLASTIC; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:BAD40654.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000417};
KW Transferase {ECO:0000313|EMBL:BAD40654.1}.
FT DOMAIN 35..147
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 214 AA; 22589 MW; 651FA1D963FF9966 CRC64;
MWLYGFARIV VGLGYRLAYR VQAEGREHIP PTGGVILCGN HINAQDPIVI GLACPRPICF
MAKEELFRSQ LLGFIIKGLG AFPVKRGSAD RAALKHALAL LEAGCCFGIF PEGTRSRTGE
LQKPEPGTAY IALKSGVPVI PVGISGSYRL FSPIRVRFGP PVDLDRFRGE KLNGETLEAA
SQAIADAIAA LLDPPSGLSN AGAGPPAGRA LSSL
//
