ID Q68IC2_HELPX Unreviewed; 179 AA.
AC Q68IC2;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Putative transposase OrfA {ECO:0000313|EMBL:AAT99185.1};
DE Flags: Fragment;
OS Helicobacter pylori (Campylobacter pylori).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=210 {ECO:0000313|EMBL:AAT99185.1};
RN [1] {ECO:0000313|EMBL:AAT99185.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HUP19 {ECO:0000313|EMBL:AAT99185.1};
RX PubMed=15516562; DOI=10.1128/JB.186.22.7508-7520.2004;
RA Kalia A., Mukhopadhyay A.K., Dailide G., Ito Y., Azuma T., Wong B.C.,
RA Berg D.E.;
RT "Evolutionary dynamics of insertion sequences in Helicobacter pylori.";
RL J. Bacteriol. 186:7508-7520(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY687751; AAT99185.1; -; Genomic_DNA.
DR AlphaFoldDB; Q68IC2; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd04761; HTH_MerR-SF; 1.
DR CDD; cd03769; SR_IS607_transposase_like; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.40.50.1390; Resolvase, N-terminal catalytic domain; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR041718; IS607_transposase-like.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR006118; Recombinase_CS.
DR InterPro; IPR006119; Resolv_N.
DR InterPro; IPR036162; Resolvase-like_N_sf.
DR InterPro; IPR048046; Transpos_IS607.
DR NCBIfam; NF033518; transpos_IS607; 1.
DR PANTHER; PTHR36172; -; 1.
DR PANTHER; PTHR36172:SF1; TRANSPOSASE IS605 ORFB C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00376; MerR; 1.
DR Pfam; PF00239; Resolvase; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SMART; SM00857; Resolvase; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR SUPFAM; SSF53041; Resolvase-like; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
DR PROSITE; PS00397; RECOMBINASES_1; 1.
DR PROSITE; PS51736; RECOMBINASES_3; 1.
PE 4: Predicted;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 5..52
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT DOMAIN 64..179
FT /note="Resolvase/invertase-type recombinase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51736"
FT ACT_SITE 72
FT /note="O-(5'-phospho-DNA)-serine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606118-50,
FT ECO:0000256|PROSITE-ProRule:PRU10137"
FT NON_TER 179
FT /evidence="ECO:0000313|EMBL:AAT99185.1"
SQ SEQUENCE 179 AA; 20773 MW; B65B01123048B9EB CRC64;
MNKRMLSIGQ ASKLLGVTIQ TLRNWDKKDL LKPDELTKGG ERRYKLESLR RINRSVVFNQ
DELKTIAYAR VSSHDQQDDL IRQVQVLELY CAKCGFNYEV IQDLGSGMNY YKKGLTKLLN
LILDNQVKRL VLTHKDRLLR FGAELVFSIC EAKEVEVVII NKGDENVRFE EELPKDVLE
//
