ID Q68Y19_RHOOP Unreviewed; 253 AA.
AC Q68Y19;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=TipAL protein {ECO:0000313|EMBL:BAD36810.1};
DE Flags: Fragment;
GN Name=TipAL {ECO:0000313|EMBL:BAD36810.1};
OS Rhodococcus opacus (Nocardia opaca).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=37919 {ECO:0000313|EMBL:BAD36810.1};
RN [1] {ECO:0000313|EMBL:BAD36810.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15268935; DOI=10.1016/j.femsle.2004.06.012;
RA Dong L., Nakashima N., Tamura N., Tamura T.;
RT "Isolation and characterization of the Rhodococcus opacus thiostrepton-
RT inducible genes tipAL and tipAS: application for recombinant protein
RT expression in Rhodococcus.";
RL FEMS Microbiol. Lett. 237:35-40(2004).
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DR EMBL; AB162018; BAD36810.1; -; Genomic_DNA.
DR AlphaFoldDB; Q68Y19; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01106; HTH_TipAL-Mta; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 1.10.490.50; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036244; TipA-like_antibiotic-bd.
DR InterPro; IPR012925; TipAS_dom.
DR PANTHER; PTHR30204:SF90; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TIPA; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF07739; TipAS; 1.
DR PRINTS; PR00040; HTHMERR.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF89082; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..73
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAD36810.1"
SQ SEQUENCE 253 AA; 28584 MW; 4AC1992705F35FA8 CRC64;
VSEKHTVGVV ARLVGVSVRT LHHYDEIGLV TPSDRTSGGY RSYSDADVER LHRVLTYREL
GFPLEEIAAL LDDPDVDALA HLRRQHALLS ERIDRLHEMA AAVEKMMEAK SMGIQLTPEE
QNEIFGDNWP GEEYAAEAEE RWGDTDAWKQ SQQRSAKMSK EDWKRIKAEG DAFEASLAQA
MADGVEPGSD RANALAEEHR AGIERFYDCD HAMQVNLAEM YLADDRFRRH YDDVAPGLAQ
YVRDVIVANA EQQ
//
