ID Q6CSF4_KLULA Unreviewed; 1151 AA.
AC Q6CSF4;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 24-JAN-2024, entry version 104.
DE SubName: Full=KLLA0D01485p {ECO:0000313|EMBL:CAH00231.1};
GN ORFNames=KLLA0_D01485g {ECO:0000313|EMBL:CAH00231.1};
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590 {ECO:0000313|EMBL:CAH00231.1, ECO:0000313|Proteomes:UP000000598};
RN [1] {ECO:0000313|EMBL:CAH00231.1, ECO:0000313|Proteomes:UP000000598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC WM37 {ECO:0000313|Proteomes:UP000000598};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
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DR EMBL; CR382124; CAH00231.1; -; Genomic_DNA.
DR RefSeq; XP_453135.1; XM_453135.1.
DR AlphaFoldDB; Q6CSF4; -.
DR STRING; 284590.Q6CSF4; -.
DR PaxDb; 284590-Q6CSF4; -.
DR GeneID; 2893032; -.
DR KEGG; kla:KLLA0_D01485g; -.
DR eggNOG; KOG0118; Eukaryota.
DR HOGENOM; CLU_276472_0_0_1; -.
DR InParanoid; Q6CSF4; -.
DR OMA; SDVMAQY; -.
DR Proteomes; UP000000598; Chromosome D.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR039171; Cwc2/Slt11.
DR InterPro; IPR018885; mRNA-bd_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR018835; RNA-binding_domain_put.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR14089; PRE-MRNA-SPLICING FACTOR RBM22; 1.
DR PANTHER; PTHR14089:SF10; RNA-BINDING PROTEIN NAB6; 1.
DR Pfam; PF10567; Nab6_mRNP_bdg; 1.
DR Pfam; PF10378; RRM; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000598};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 647..715
FT /note="RRM"
FT /evidence="ECO:0000259|SMART:SM00360"
FT REGION 125..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 849..886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..970
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1018..1041
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..205
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1151 AA; 128497 MW; 82CF6CBF2692531B CRC64;
MNSGTSANHY QPSLIYGRPP VGYEQQVYDV AGRNGGSNHH PPQYIYYTHR GGSMPGSIPG
SIPGTVSIPQ TPFDPVYGIT LLPSHLLVGS PFVNTPQTGG PMSAGTGANG VPVGSNNIMN
LRNSSYKSFY PPAPKLRPAP SGRLRRARRK DNKPQQQREH SRDNNKVEAE YDVERGYSSR
SASRSQSFSA STSGSMSGSS GPKSIRKTID SELKIQFQYS ILPKGNDTYR SRSLLFTNVN
SELDIVEFLQ KVAKNYPIES IYLIKDEDTG DDIENLNTSN NDDDPNQNYN ADNNNNSKRE
DDKDKESAPA LTKQIAISPS SCSQQSYLLS FFTKESCLDF YNNLLQRYAE IKNAVKSDQL
AMNFVKIQDD EEWMANLKMN VISLGATRSL YVEFADDSVT SDTIWDTLPF LKNSGKYVVI
DVDVVTTDER RKNFGLHYCL LHFLSVTMAL EVKELLETGD EAVSRVSFVT PANSADKEMR
RRRSSAISLK QEASPQMFST DSRSRSRSSN VSLPLSEQVS TASTDISTPI YEEFDGNLTW
STLIVDVSEY KEPIVNEFDH HLNSWSISKP TTLYMHESGT TNFSSSNLSD DIDPLSISSH
DPVPQQMLLN EYPYIMEPLM PPQITQTIQN QYSKSIQAVN AGMEHRTVYI GNINPRSKAE
DICNVVRGGI LQHIKWVSHK RICFVTFIET AAAVQFYANT TLEPIILHGN VLKVGWGQNP
GPLPKNIALA VTVGASRNVY VSLPDKAFKD KFINDPQFKE YQNRYKIPNI AQLKSDFGAY
GTMEQVNFHS DGHCCWINFM NISSAIKLVE EYSDTKDNLF HKKTEGRYVG LIIGYGKDRC
GNINRNLVFN KNGKGSNHNR NSQNNNTSRG HRQRKQSATF SNASNIDLKH SSVANASIAN
GKLDRPMDNK NFLSLGVDAD FSEGLGISIS PQAERRHVLS DNEDEREEHR EEEQEECGNR
HSGVNGSNVA NNEAINETLI NGTYTADIPE DTLQVGSDSC STYSGSSSSD VDIIVNAPSP
KAGDAKSFTH TRRNAHHRQR NTNQTRQYNN HHHAQQHQFQ PLSHINAPYQ TPQPQYHPYP
QTPHRFSNSF VPVAQHEGAN NGNPRKSSMK PIAGSDVMTR YLEQLHHNTF VYAANILGAT
QDPVFYDEDN A
//
