ID Q6CUW3_KLULA Unreviewed; 304 AA.
AC Q6CUW3;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 24-JAN-2024, entry version 104.
DE SubName: Full=KLLA0C01804p {ECO:0000313|EMBL:CAH01127.1};
GN ORFNames=KLLA0_C01804g {ECO:0000313|EMBL:CAH01127.1};
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590 {ECO:0000313|EMBL:CAH01127.1, ECO:0000313|Proteomes:UP000000598};
RN [1] {ECO:0000313|EMBL:CAH01127.1, ECO:0000313|Proteomes:UP000000598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC WM37 {ECO:0000313|Proteomes:UP000000598};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Endosome membrane {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the VTA1 family.
CC {ECO:0000256|ARBA:ARBA00007895}.
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DR EMBL; CR382123; CAH01127.1; -; Genomic_DNA.
DR RefSeq; XP_452276.1; XM_452276.1.
DR AlphaFoldDB; Q6CUW3; -.
DR STRING; 284590.Q6CUW3; -.
DR PaxDb; 284590-Q6CUW3; -.
DR GeneID; 2892367; -.
DR KEGG; kla:KLLA0_C01804g; -.
DR eggNOG; ENOG502RXP8; Eukaryota.
DR HOGENOM; CLU_063501_0_0_1; -.
DR InParanoid; Q6CUW3; -.
DR OMA; YCKIYVL; -.
DR Proteomes; UP000000598; Chromosome C.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.420; Immunoglobulin FC, subunit C; 1.
DR Gene3D; 1.25.40.270; Vacuolar protein sorting-associated protein vta1; 1.
DR InterPro; IPR044538; Vta1-like.
DR InterPro; IPR039431; Vta1/CALS_N.
DR InterPro; IPR023175; Vta1/CALS_N_sf.
DR InterPro; IPR041212; Vta1_C.
DR PANTHER; PTHR46009; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG; 1.
DR PANTHER; PTHR46009:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG; 1.
DR Pfam; PF04652; Vta1; 1.
DR Pfam; PF18097; Vta1_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000000598};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 8..153
FT /note="Vta1/callose synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04652"
FT DOMAIN 263..299
FT /note="Vta1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18097"
FT REGION 154..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 304 AA; 34659 MW; F322776F06A20001 CRC64;
MSNVAQYKRV IKLSKELSTL PVISYYLKLY AAELILNEKE RDGEATELVM SLLDDVESFK
NEVNDEGTKI LLNEKDKALA FVLNLAMSIY NGILVQIQDD RINDDIGKGL WCCIDLFQCC
KHIWADSMDA IVKEQCDKRI KHSKYYLMKL KRGQLQSDKK PQETTSEPTN SNPLSEVEDE
IPNFVEDLED QPLFEEPKDS EIAQQHGPSP SLKVDESVEK LKQLESPEVP IKLLTPEPIK
LESPKPAVRH DVATLKEIMS REHRIQKAQR SAKYAISALN YDDIVTAKAE LLQAFKLLED
LTPE
//
