ID Q6DIR2_XENTR Unreviewed; 746 AA.
AC Q6DIR2;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=SILV protein {ECO:0000313|EMBL:AAH75473.1};
DE Flags: Fragment;
GN Name=SILV {ECO:0000313|EMBL:AAH75473.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAH75473.1};
RN [1] {ECO:0000313|EMBL:AAH75473.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH75473.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
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DR EMBL; BC075473; AAH75473.1; -; mRNA.
DR AlphaFoldDB; Q6DIR2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861:SF1; MELANOCYTE PROTEIN PMEL; 1.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..746
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004272207"
FT TRANSMEM 672..696
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 265..296
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 116..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 315..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAH75473.1"
SQ SEQUENCE 746 AA; 79230 MW; D2D3AB14A134D349 CRC64;
IRKQRMKGVY GLVVFWVLCA GAETQNWSQN RVQQMNQQVA GNRQPPFKSW NSRMYPIWRG
TEAQKKNCWK GGQVTFNLVN DAPTLTGAKA TFSIQLNFPK NQTVLPDGQV VWGQNRTDNG
TWVPSGDPVY PDESTEGSEC TFPDGRPFPR GSEKKRSKFV YVWQTLGKYW QVVDGPSSNL
TLETDGIPLG SYTMQVVVYH YRGRQKFIPI GSASSQFTIT DQIPVSVSIS QLLDLDQEDQ
RFIQNRAVSF AVSIHDPSHY LQAADISFSW DFGDQSGTLI TRNTDVTHTY VSPGVFRPKV
VLQAAIPITP CGSTAAAGTA EPVPSTVIPP QPTTTAVSTS GGQVTDAPTG TPAVLPGNVT
EPQGTINVIV VTLPSEETQN NLAAEATSSV SASALPDNEA ATLPEGTEEE AGVTDAAEET
VPEEVEAVPN QEQAAEAVPS QGAVTVAEAV PSQEAEAVPS QEAEAVAEAV PSQEAVSEAV
PSQEAVEAVT SEAGNTEAGA ELAEETPSVA SEINELPGST AEVVTVPATE GPEEVVVIAK
RQAPEDPLVG CLLYRYGTFA TDLDIVQGIE SAQIVQVAPV AAVDGTENAV DLTVTCQGSV
PSQVCTIISG PDCSTPQETI CNTVQPSTDC QLVLRQVFND TGLYCVNVSL TDAVSLAMAS
TQVSVSGAGS SFANGGIVIV GVLLAVFAVV VVAYAYRQKK SYTTLRTAQP PTSWFPERLS
LRLFFQNALG LSRSGENSPL LNGRVV
//
