ID Q6DJ37_XENTR Unreviewed; 388 AA.
AC Q6DJ37; F7E9Q9;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};
GN Name=LOC448276 {ECO:0000313|RefSeq:NP_001006126.1,
GN ECO:0000313|Xenbase:XB-GENE-29098943};
GN Synonyms=b3galt2 {ECO:0000313|EMBL:AAH75347.1}, b3galt2l
GN {ECO:0000313|Ensembl:ENSXETP00000009847};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAH75347.1};
RN [1] {ECO:0000313|RefSeq:NP_001006126.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH75347.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:AAH75347.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000009847}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000009847};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000009847}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001006126.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein
CC {ECO:0000256|RuleBase:RU363063}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661, ECO:0000256|RuleBase:RU363063}.
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DR EMBL; BC075347; AAH75347.1; -; mRNA.
DR RefSeq; NP_001006126.1; NM_001006126.1.
DR STRING; 8364.ENSXETP00000036274; -.
DR CAZy; GT31; Glycosyltransferase Family 31.
DR PaxDb; 8364-ENSXETP00000009847; -.
DR PaxDb; 8364-ENSXETP00000016483; -.
DR DNASU; 448276; -.
DR Ensembl; ENSXETT00000009847; ENSXETP00000009847; ENSXETG00000004536.
DR Ensembl; ENSXETT00000110798; ENSXETP00000102819; ENSXETG00000004536.
DR Ensembl; ENSXETT00000110953; ENSXETP00000111810; ENSXETG00000004536.
DR GeneID; 448276; -.
DR KEGG; xtr:448276; -.
DR AGR; Xenbase:XB-GENE-5795334; -.
DR Xenbase; XB-GENE-5795334; b3galt2l.
DR Xenbase; XB-GENE-29098943; LOC448276.
DR eggNOG; KOG2287; Eukaryota.
DR HOGENOM; CLU_036849_2_1_1; -.
DR OMA; IVTSHQF; -.
DR OrthoDB; 532757at2759; -.
DR TreeFam; TF318639; -.
DR Proteomes; UP000008143; Chromosome 4.
DR Bgee; ENSXETG00000004536; Expressed in heart and 7 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR045821; B3GT2_N.
DR InterPro; IPR002659; Glyco_trans_31.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR11214:SF19; BETA-1,3-GALACTOSYLTRANSFERASE 2; 1.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR Pfam; PF19341; B3GALT2_N; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363063,
KW ECO:0000313|EMBL:AAH75347.1};
KW Golgi apparatus {ECO:0000256|RuleBase:RU363063};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363063};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968,
KW ECO:0000256|RuleBase:RU363063};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AAH75347.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363063};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363063}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363063"
FT DOMAIN 69..133
FT /note="Beta-1,3-galactosyltransferase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19341"
SQ SEQUENCE 388 AA; 45800 MW; 35743104E03B7BF6 CRC64;
MSSWRRRHCF PLGWNWHTRR FMFHCFVLLV LFFFMFVLFH NNRWLPRQIM DKGIIQVDNT
NSFQSKESET ISKMLQKLVV FSLKNNRSYH KKVLRQRVTT AEITSNRVSQ NTLHYGYIIN
EPDKCQKSTP FLILLIAVEP QQLSAREAIR QTWGKEDLFH GILIVKLFLL GRDSKGTDRT
DQAIVDESNQ YHDIIQQDYL DTYNNLTIKT LMGMHWIATF CPNVSYIMKT DSDMFVNTEH
LIYRLLKPDA APQTNYFTGY FMKGYAPNRN KNSKWYMPPE LYPGDLYPPF CSGTGYVFSG
DLAEKIYKVS LSIPRLHLED VYIGVCLEKL GIKPVPPPKE SYFNIWRVYY SDCVYNQIVT
SHQFQPSELL KYWNQLQQNR HVCSKTPK
//
