ID   Q6J5G9_HAEIF            Unreviewed;       185 AA.
AC   Q6J5G9;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   24-JAN-2024, entry version 59.
DE   SubName: Full=Tryptophanase TnaA {ECO:0000313|EMBL:AAT40777.1};
DE   Flags: Fragment;
GN   Name=tnaA {ECO:0000313|EMBL:AAT40777.1};
OS   Haemophilus influenzae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727 {ECO:0000313|EMBL:AAT40777.1};
RN   [1] {ECO:0000313|EMBL:AAT40777.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15908377; DOI=10.1128/IAI.73.6.3479-3491.2005;
RA   Shen K., Antalis P., Gladitz J., Sayeed S., Ahmed A., Yu S., Hayes J.,
RA   Johnson S., Dice B., Dopico R., Keefe R., Janto B., Chong W., Goodwin J.,
RA   Wadowsky R.M., Erdos G., Post J.C., Ehrlich G.D., Hu F.Z.;
RT   "Identification, distribution, and expression of novel genes in 10 clinical
RT   isolates of nontypeable Haemophilus influenzae.";
RL   Infect. Immun. 73:3479-3491(2005).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC       {ECO:0000256|ARBA:ARBA00009721}.
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DR   EMBL; AY599433; AAT40777.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6J5G9; -.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          39..149
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAT40777.1"
SQ   SEQUENCE   185 AA;  20596 MW;  6F41E51E63C272BD CRC64;
     EEVYHECRTL CVVQEGFPTY GGLEGGAMER LAVGLHDGMR QEWLAYRIAQ IEYLVAGLEK
     IGVPCQQPGG HAAFVDAGKL LPHIPADQFP AQALSCELYK VAGIRAVEIG SFLLGRDPKT
     GKQLPCPAEL LRLTIPRATY TQTHMDFIIE AFQKVKENAE NIKGLTFTYE PKVLRHFTAR
     LKEVE
//