ID Q6JLA5_9VIRU Unreviewed; 340 AA.
AC Q6JLA5;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=3-beta hydroxysteroid dehydrogenase/isomerase family {ECO:0000313|EMBL:AAS47817.1};
OS Lymphocystis disease virus - isolate China.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Iridoviridae; Alphairidovirinae; Lymphocystivirus;
OC Lymphocystis disease virus 2.
OX NCBI_TaxID=256729 {ECO:0000313|EMBL:AAS47817.1, ECO:0000313|Proteomes:UP000106699};
RN [1] {ECO:0000313|EMBL:AAS47817.1, ECO:0000313|Proteomes:UP000106699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15194775; DOI=10.1128/JVI.78.13.6982-6994.2004;
RA Zhang Q.Y., Xiao F., Xie J., Li Z.Q., Gui J.F.;
RT "Complete genome sequence of lymphocystis disease virus isolated from
RT China.";
RL J. Virol. 78:6982-6994(2004).
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219, ECO:0000256|RuleBase:RU004475}.
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DR EMBL; AY380826; AAS47817.1; -; Genomic_DNA.
DR RefSeq; YP_077167.1; NC_005902.1.
DR GeneID; 2943450; -.
DR KEGG; vg:2943450; -.
DR OrthoDB; 8536at10239; -.
DR Proteomes; UP000106699; Genome.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:AAS47817.1};
KW Oxidoreductase {ECO:0000256|RuleBase:RU004475};
KW Reference proteome {ECO:0000313|Proteomes:UP000106699}.
FT DOMAIN 5..268
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 340 AA; 39270 MW; CB889ADA1B09639F CRC64;
MIKFMVIGGH GFLGKSVTKH LITCCTRVGE IRLFDIKERN IWWNDSRINF IKGSIEDRSA
LIDAMRDIDV VFHCAQAKTD KSVLKIEAVN YSGTLNVINA CLLCNVKCLI YAGSFCFNKY
GDYFYRGDEY SDYYRIFDDT YAKTKHMAEV NVIKADRSKT VLGKILRTCS IQSFGVYGEE
DSRFEKIFTK AFESGTVLGL CYNKIIQQSR TYVGNLAWMH ISAYKILYNT NKADRAGGQI
YFAYDYSPCV CPDDFDLLFL SEFNISLKIM SKRFLKATAR INDLMTKMGK KQYFGSNELK
KYNTYCVFET SKAKEELEYN PLYTWTDSKY SVITWLLTLI
//
