ID Q6LGP0_PHOPR Unreviewed; 407 AA.
AC Q6LGP0;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Multidrug resistance efflux pump {ECO:0000313|EMBL:CAG23540.1};
GN Name=VVA1251 {ECO:0000313|EMBL:CAG23540.1};
GN OrderedLocusNames=PBPRB1680 {ECO:0000313|EMBL:CAG23540.1};
OS Photobacterium profundum (strain SS9).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=298386 {ECO:0000313|EMBL:CAG23540.1, ECO:0000313|Proteomes:UP000000593};
RN [1] {ECO:0000313|Proteomes:UP000000593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1253 / SS9 {ECO:0000313|Proteomes:UP000000593};
RX PubMed=15746425; DOI=10.1126/science.1103341;
RA Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA Bartlett D.H., Valle G.;
RT "Life at depth: Photobacterium profundum genome sequence and expression
RT analysis.";
RL Science 307:1459-1461(2005).
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DR EMBL; CR378680; CAG23540.1; -; Genomic_DNA.
DR RefSeq; WP_011221696.1; NC_006371.1.
DR AlphaFoldDB; Q6LGP0; -.
DR STRING; 298386.PBPRB1680; -.
DR KEGG; ppr:PBPRB1680; -.
DR eggNOG; COG1566; Bacteria.
DR HOGENOM; CLU_018816_15_3_6; -.
DR Proteomes; UP000000593; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 29..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..113
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 220..321
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 407 AA; 45657 MW; E5DB442415FD9532 CRC64;
MLEGLAVWAL FIYLLRLVGM PWNKYSKSFS YLGGTGWLMF VWVGLITFAP MDLSGGSLVQ
SPHIQLRPGS TKIKGHVKAI YVSPNEKVKE GQLIYEIDDE PYVIAKNKAE SLLNSAEVSL
SISKEDARIS ESSYQASLKD IEISKNEISA AEEDLRWKQT TYNRYIEQNK VVNHTITESM
LDEQSTAVEV AKAKKITLVS QLDKSILSAS KAKLDFEKSQ LNVNSHEVDV VTEQENVAQA
QWNLDNTKVH APADGYLTNF IMREGQYVGV MPRIQMYTEE KYVLMRVNHQ AIRNVKSGQM
AEFTSAVYPG KVFNAEVEGI IEATGESQGS LLARDDNVRQ VTGANVANKY HFVRLKLYET
GGYDIPVGSV GLAWISTEKP IGFLGFLDVV RGIIIRMKSQ IFYIWSM
//
