ID COAE_PHOPR Reviewed; 200 AA.
AC Q6LMG7;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 01-MAY-2013, entry version 60.
DE RecName: Full=Dephospho-CoA kinase;
DE EC=2.7.1.24;
DE AltName: Full=Dephosphocoenzyme A kinase;
GN Name=coaE; OrderedLocusNames=PBPRA3204;
OS Photobacterium profundum (Photobacterium sp. (strain SS9)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC Vibrionaceae; Photobacterium.
OX NCBI_TaxID=74109;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SS9;
RX PubMed=15746425; DOI=10.1126/science.1103341;
RA Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N.,
RA Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N.,
RA Romualdi C., Bartlett D.H., Valle G.;
RT "Life at depth: Photobacterium profundum genome sequence and
RT expression analysis.";
RL Science 307:1459-1461(2005).
CC -!- FUNCTION: Catalyzes the phosphorylation of the 3'-hydroxyl group
CC of dephosphocoenzyme A to form coenzyme A (By similarity).
CC -!- CATALYTIC ACTIVITY: ATP + 3'-dephospho-CoA = ADP + CoA.
CC -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from
CC (R)-pantothenate: step 5/5.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the CoaE family.
CC -!- SIMILARITY: Contains 1 DPCK (dephospho-CoA kinase) domain.
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DR EMBL; CR378673; CAG21510.1; -; Genomic_DNA.
DR RefSeq; YP_131312.1; NC_006370.1.
DR ProteinModelPortal; Q6LMG7; -.
DR STRING; 298386.PBPRA3204; -.
DR EnsemblBacteria; CAG21510; CAG21510; PBPRA3204.
DR GeneID; 3123331; -.
DR KEGG; ppr:PBPRA3204; -.
DR PATRIC; 22937473; VBIPhoPro109272_3352.
DR eggNOG; COG0237; -.
DR HOGENOM; HOG000020769; -.
DR KO; K00859; -.
DR OMA; QRLACQM; -.
DR UniPathway; UPA00241; UER00356.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:HAMAP.
DR GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR HAMAP; MF_00376; Dephospho_CoA_kinase; 1; -.
DR InterPro; IPR001977; Depp_CoAkinase.
DR Pfam; PF01121; CoaE; 1.
DR TIGRFAMs; TIGR00152; TIGR00152; 1.
DR PROSITE; PS51219; DPCK; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW Kinase; Nucleotide-binding; Transferase.
FT CHAIN 1 200 Dephospho-CoA kinase.
FT /FTId=PRO_0000172974.
FT DOMAIN 4 200 DPCK.
FT NP_BIND 9 16 ATP (Potential).
SQ SEQUENCE 200 AA; 22058 MW; 7BFC6A0BF3014750 CRC64;
MTMVIGLTGG IGSGKTTVAN LFGDYGIDII DADIIAREVV EPNTTGLNAI VDKLGADILL
TDGTLDRSKL RNAIFNQQQL KDWLNGLLHP LIREKMLSNI SKATSPYCLL VVPLMVENNL
QTMTHRLLVV DVDESVQIDR TQARDNVAPE HVKKILMAQA SRQNRNAAAD DIISNNGNSA
ELKNKVAELH QKYIKMSHLY
//
