ID   Q6LNJ4_PHOPR            Unreviewed;       228 AA.
AC   Q6LNJ4;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE            EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN   Name=XCC3360 {ECO:0000313|EMBL:CAG21132.1};
GN   OrderedLocusNames=PBPRA2760 {ECO:0000313|EMBL:CAG21132.1};
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386 {ECO:0000313|EMBL:CAG21132.1, ECO:0000313|Proteomes:UP000000593};
RN   [1] {ECO:0000313|Proteomes:UP000000593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9 {ECO:0000313|Proteomes:UP000000593};
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC         Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC         Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR   EMBL; CR378672; CAG21132.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6LNJ4; -.
DR   STRING; 298386.PBPRA2760; -.
DR   KEGG; ppr:PBPRA2760; -.
DR   eggNOG; COG0693; Bacteria.
DR   HOGENOM; CLU_070319_2_0_6; -.
DR   Proteomes; UP000000593; Chromosome 1.
DR   CDD; cd03141; GATase1_Hsp31_like; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR002818; DJ-1/PfpI.
DR   PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR   PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR   Pfam; PF01965; DJ-1_PfpI; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000593};
KW   Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT   DOMAIN          28..223
FT                   /note="DJ-1/PfpI"
FT                   /evidence="ECO:0000259|Pfam:PF01965"
SQ   SEQUENCE   228 AA;  24543 MW;  55B5C03466C226D6 CRC64;
     MMMKILMVLT SHDKLGDTDH KTGFWIEEFA APYYRFLDEN ADITLASPAG GQPPIDPNSE
     LEQSQTEATV RFNSDEQAQA VLANTRKLSD VSEQDYDAVF YSGGHGPLWD LVSDSDSIAL
     IEAFWQAGKP VSAVCHAPAV LLNAKTADGE YIISGKAVTG FTNSEETAVG LAEVVPFLLE
     DELKSRGGQF ESAQDWNSLA IQDGMLITGQ NPASSEAVAE ALLSLLAK
//