ID Q6P500_RAT Unreviewed; 390 AA.
AC Q6P500;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Coxsackie virus and adenovirus receptor-like 1 {ECO:0000313|EMBL:AAH63181.1};
GN Name=Cxadrl1 {ECO:0000313|EMBL:AAH63181.1, ECO:0000313|RGD:735201};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|EMBL:AAH63181.1};
RN [1] {ECO:0000313|EMBL:AAH63181.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Pituitary gland {ECO:0000313|EMBL:AAH63181.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC {ECO:0000256|ARBA:ARBA00004536}. Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}.
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DR EMBL; BC063181; AAH63181.1; -; mRNA.
DR RefSeq; NP_955438.1; NM_199406.2.
DR AlphaFoldDB; Q6P500; -.
DR GeneID; 361873; -.
DR KEGG; rno:361873; -.
DR UCSC; RGD:735201; rat.
DR AGR; RGD:735201; -.
DR CTD; 361873; -.
DR RGD; 735201; Cxadrl1.
DR OrthoDB; 3027035at2759; -.
DR PhylomeDB; Q6P500; -.
DR GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44468:SF4; CAR-LIKE SOLUBLE PROTEIN; 1.
DR PANTHER; PTHR44468; COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED; 1.
DR Pfam; PF07686; V-set; 3.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 2: Evidence at transcript level;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Receptor {ECO:0000313|EMBL:AAH63181.1}; Signal {ECO:0000256|SAM:SignalP};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..390
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004278263"
FT DOMAIN 34..123
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 127..264
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 268..387
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 390 AA; 43059 MW; 8860C7B7AFDA179B CRC64;
MALLLGFLFF CGVTDLIGSV SITTPEQIVQ EAGGEIVHLP CMFTLSPEDQ GPLDIEWLRL
SGPNNEAIDH VVILYAADKI YSDFYQDLKG RVHFTSNDVV SGDASIKIRN VRPADSGTYQ
CKVKKAPGVA KTTVQLTVID ITGSVNITTP EQTVQEAQGE IVHLPCIFTY VSKDQGPLDV
EWLRLSGPNN EAIDHVVILY SADKIHDDVY PDLKGRVYFT SNDIRSGDAS INITNVRLSD
VGTYQCKVKT YPGIVNRNLQ LAVTNILGSV SITTPEQTIQ KARGETVHLP CMFTLIPEDR
GPLFIDWIQL TGPQNEVVNR MFIVYLADKV YDNFYQDMKG RVYFTNNDVR SGDASINITN
VQLSDAGTYQ CGVSHDFGTA QRTIQLTVVG
//
