ID Q6P854_XENTR Unreviewed; 319 AA.
AC Q6P854; F7CWP9;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 133.
DE SubName: Full=High mobility group 20B {ECO:0000313|Ensembl:ENSXETP00000047800};
DE SubName: Full=High-mobility group 20A {ECO:0000313|EMBL:AAH61376.1};
DE SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|RefSeq:NP_988941.1};
GN Name=hmg20b {ECO:0000313|Ensembl:ENSXETP00000047800,
GN ECO:0000313|RefSeq:NP_988941.1, ECO:0000313|Xenbase:XB-GENE-5809048};
GN Synonyms=hmg20a {ECO:0000313|EMBL:CAJ83818.1}, MGC75938
GN {ECO:0000313|EMBL:AAH61376.1};
GN ORFNames=TGas142e24.1-001 {ECO:0000313|EMBL:CAJ83818.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAH61376.1};
RN [1] {ECO:0000313|RefSeq:NP_988941.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH61376.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH61376.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CAJ83818.1}
RP NUCLEOTIDE SEQUENCE.
RA Amaya E., Ashurst J.L., Bonfield J.K., Croning M.D.R., Chen C-K.,
RA Davies R.M., Francis M.D., Garrett N., Gilchrist M.J., Grafham D.V.,
RA McLaren S.R., Papalopulu N., Rogers J., Smith J.C., Taylor R.G., Voigt J.,
RA Zorn A.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSXETP00000047800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000047800};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [5] {ECO:0000313|Ensembl:ENSXETP00000047800}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [6] {ECO:0000313|RefSeq:NP_988941.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC061376; AAH61376.1; -; mRNA.
DR EMBL; CR761881; CAJ83818.1; -; mRNA.
DR RefSeq; NP_988941.1; NM_203610.1.
DR DNASU; 394538; -.
DR Ensembl; ENSXETT00000047800; ENSXETP00000047800; ENSXETG00000022092.
DR GeneID; 394538; -.
DR KEGG; xtr:394538; -.
DR AGR; Xenbase:XB-GENE-5809048; -.
DR CTD; 10362; -.
DR Xenbase; XB-GENE-5809048; hmg20b.
DR HOGENOM; CLU_060006_1_0_1; -.
DR OrthoDB; 37141at2759; -.
DR Proteomes; UP000008143; Chromosome 1.
DR Bgee; ENSXETG00000022092; Expressed in testis and 15 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22018; HMG-box_HMG20B; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR46040; HIGH MOBILITY GROUP PROTEIN 2; 1.
DR PANTHER; PTHR46040:SF2; SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1-RELATED; 1.
DR Pfam; PF00505; HMG_box; 1.
DR PRINTS; PR00886; HIGHMOBLTY12.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 68..136
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 68..136
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 35..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 198..253
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 35..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 36745 MW; B34D15E9CD9B7C4B CRC64;
MSQPTKHLHG ILHPVTKTQG GNFLVAVKQE KIDVQRAGDK NTGGEEEPVK KRGWPKGKKR
KKILPNGPKA PVTGYVRFLN ERREQIRAQH PDLPFPEITK MLGAEWSTLP PHEKQRYLDE
AERDKQQYMK ELREYQQSEA YKMCAEKIQE KKIKKEETSV AAASTLLNGH THKTGDSQSD
GFSSFDVTIF TEEFLDQNKV REAELRRLRK MNMEFEEQNS ILQRHTESMN CAKERLEQEL
AQEERQTIVL QQQLQTIRQI LLSSFSSLPI PGTGETPTLG NLDVYMAKLH NLIEGNPTQH
EKLVMKIKEV LSRINSDHL
//
