GenomeNet

Database: UniProt
Entry: Q6PCR6
LinkDB: Q6PCR6
Original site: Q6PCR6 
ID   ZFR_DANRE               Reviewed;        1074 AA.
AC   Q6PCR6;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   01-OCT-2014, entry version 69.
DE   RecName: Full=Zinc finger RNA-binding protein;
GN   Name=zfr;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in postimplantation and gastrulation stages of
CC       development. Binds to DNA and RNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Contains 1 DZF domain. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH59198.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; BC059198; AAH59198.1; ALT_INIT; mRNA.
DR   RefSeq; NP_955852.1; NM_199558.1.
DR   UniGene; Dr.26724; -.
DR   ProteinModelPortal; Q6PCR6; -.
DR   STRING; 7955.ENSDARP00000069275; -.
DR   GeneID; 321659; -.
DR   KEGG; dre:321659; -.
DR   CTD; 51663; -.
DR   ZFIN; ZDB-GENE-030131-378; zfr.
DR   eggNOG; NOG292385; -.
DR   HOGENOM; HOG000232147; -.
DR   HOVERGEN; HBG108765; -.
DR   InParanoid; Q6PCR6; -.
DR   KO; K13203; -.
DR   PhylomeDB; Q6PCR6; -.
DR   NextBio; 20807476; -.
DR   PRO; PR:Q6PCR6; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   InterPro; IPR006561; DZF.
DR   InterPro; IPR007087; Znf_C2H2.
DR   InterPro; IPR015880; Znf_C2H2-like.
DR   InterPro; IPR003604; Znf_U1.
DR   Pfam; PF07528; DZF; 1.
DR   SMART; SM00572; DZF; 1.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   SMART; SM00451; ZnF_U1; 3.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
PE   2: Evidence at transcript level;
KW   Complete proteome; Cytoplasm; Developmental protein; DNA-binding;
KW   Nucleus; Reference proteome; Repeat; RNA-binding.
FT   CHAIN         1   1074       Zinc finger RNA-binding protein.
FT                                /FTId=PRO_0000312723.
FT   DOMAIN      697   1073       DZF.
FT   COMPBIAS     35    109       Ala-rich.
FT   COMPBIAS    418    488       Ser-rich.
FT   COMPBIAS    679    714       Pro-rich.
SQ   SEQUENCE   1074 AA;  116523 MW;  3401EB8F7AF55E3C CRC64;
     MIPICPVVSF TYVPSRLGED AKMATGNYFG FTHGAGAQYS QQPAAGVAYT HPTTVASYTV
     HQAPVAAHTV AAAYAPTAAT VAVARPAPVA VAAAANAAAF GGYQPAHAAT DYGYAQRQPE
     VPPPPPPVTS QNYQDSYSYV RSTAPAVAYD SKQYYQQPAA TPAVAAAAAQ PQPTVAESYY
     QTAPKTGYSQ GATPYTQTQQ TRQVTVVKPA TPSPATSTFS IYPVSSAVQP VAAAAAASVV
     PSYSQSPTYS TNAVTYSGTS YSGYEAAVYS AASSYYQQQQ QQQKQAAVAA AATAAWTGST
     FTKKTPFQNK TLKPKQPPKP PQIHYCDVCK ISCAGPQTYK EHLEGQKHKK KEAALKVSQS
     SSSSSGGGSS ARGTQNQLRC ELCDVSCTGA DAYAAHIRGA KHQKVVKLHT KLGKPIPSTE
     PSVVSQSSTS STAAPNKTSS SNINSSTSTS SNASSSVSAS YLKSGSMAAS AAQGKSSGAN
     NVSVNSSSIK KVNTPKINFV GGNKLQTTAS KSDESKADAA KTAQSAASAP AADAKNDMPD
     PMSPQSALAA LQSDVQPVGH DYVEEVRNDE GKVIRFHCKL CECSFNDPNA KEMHLKGRRH
     RLQYKKKVNP DLQVEVKPSI RARKIQEEKM RKQMQKEEYW RRREEEERWR MEMRRYEEDM
     YWRRMEEEQH HWEDRRRMPD GGYPQGPPGP PGLLGVRPGM PIPQPQGPVP PRRPDSSDDR
     YVMTKHAAIY PSEDELQAIQ KIVSITERAL KLVSDIITDQ DAGASAKGKE EDKEKKEPPK
     DRLLKGVMRV GVLAKGLLLR GDKEVNLVLL CSEKPTKNLL TRIVEHLPKQ LTMVTPEKYE
     VKGSIQESAI ILTSCGDPKM QVTITLTSPI IREESSRDGD VTSSMVKDPA DVLDRQKCLD
     ALAALRHAKW FQARANGLQS CVIVIRILRD LCQRVPTWSA FPSWAMELLV EKAISSASGP
     MSPGDALRRV FECISSGILL SGAPGLIDPC EKNPTDTLAF MEEQQREDIT SSAQFALRLL
     AFRQIHKVLG MDPLPQMNSR FNVRNTRKRR RDNSDGADGF EAEGKKDKKD YEGF
//
DBGET integrated database retrieval system