ID   Q6SH17_9BACT            Unreviewed;       515 AA.
AC   Q6SH17;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Phytoene dehydrogenase {ECO:0000313|EMBL:AAR37802.1};
DE            EC=1.14.99.- {ECO:0000313|EMBL:AAR37802.1};
GN   Name=crtI {ECO:0000313|EMBL:AAR37802.1};
GN   ORFNames=MBMO_EBAC000-63A02.81 {ECO:0000313|EMBL:AAR37802.1};
OS   uncultured marine bacterium 442.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=257392 {ECO:0000313|EMBL:AAR37802.1};
RN   [1] {ECO:0000313|EMBL:AAR37802.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., DeLong E.F.;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAR37802.1}
RP   NUCLEOTIDE SEQUENCE.
RA   DeLong E.F.;
RT   "Monterey Bay Coastal Ocean Microbial Observatory environmental clone
RT   sequencing.";
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- PATHWAY: Carotenoid biosynthesis. {ECO:0000256|ARBA:ARBA00004829,
CC       ECO:0000256|RuleBase:RU362075}.
CC   -!- SIMILARITY: Belongs to the carotenoid/retinoid oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00006046, ECO:0000256|RuleBase:RU362075}.
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DR   EMBL; AY458639; AAR37802.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6SH17; -.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR014105; Carotenoid/retinoid_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR008150; Phytoene_DH_bac_CS.
DR   NCBIfam; TIGR02734; crtI_fam; 1.
DR   PANTHER; PTHR43734:SF3; B-CAROTENE KETOLASE; 1.
DR   PANTHER; PTHR43734; PHYTOENE DESATURASE; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS00982; PHYTOENE_DH; 1.
PE   3: Inferred from homology;
KW   Carotenoid biosynthesis {ECO:0000256|ARBA:ARBA00022746,
KW   ECO:0000256|RuleBase:RU362075};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU362075,
KW   ECO:0000313|EMBL:AAR37802.1}.
FT   DOMAIN          32..500
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   515 AA;  57830 MW;  AC383E0472DA5681 CRC64;
     MNTQLDLAKL GTQNYGPLDE RPHAIVIGSG FGGLAAAVRL GARGYRVTIL EKLDAAGGRA
     YVYHQDGFTF DAGPTIITAP FLLEELWELC GRKLSDDVDL RPMDPFFRIR FDDGRSFDYS
     GDRESNIEQI KTFNEADAEG YLKYLDASEQ RYRVGFERLG FKSFDSLWQL IRFLPQLIRL
     RSDRSVYSLV SSYIKDPYLR QVMSFHPLLI GGNPFSVTGI YSLISHLEQS FGVWSAMGGT
     GRLVDGFVSL IEGQGSHIFY NTEVAQINTE GRRATGVTLK TGETLNADIV VSNADSAWTY
     RHLLPENKRK RWTNKRLDKA AYSNGLFVWY FGTQGRYEDV PHHSVLLGPR YEGLLKDIFK
     HKVLSDDFSL YLHRPTATDS SMAPEGCDTF YALVPVPHLD AGVDWLEHAE TFRQAIETRL
     AETVLPDISN RIMTSRLLTP LDFQDRLNSF KGAGFSFEPR ISQSAWFRPH NQSEDFDGLY
     LVGAGTHPGA GIPGVISSAK VLDEVVPHAT TIRTR
//