ID Q6T2W7_9BACT Unreviewed; 268 AA.
AC Q6T2W7;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=CmuA {ECO:0000313|EMBL:AAS17533.1};
DE Flags: Fragment;
GN Name=cmuA {ECO:0000313|EMBL:AAS17533.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:AAS17533.1};
RN [1] {ECO:0000313|EMBL:AAS17533.1}
RP NUCLEOTIDE SEQUENCE.
RA Miller L.G., Warner K.L., Baesman S.M., Oremland R.S., McDonald I.R.,
RA Radajewski S., Murrell C.;
RT "Degradation of methyl bromide and methyl chloride in soil microcosms: Use
RT of stable C isotope fractionation and stable isotope probing to identify
RT reactions and the responsible microorganisms.";
RL Geochim. Cosmochim. Acta 0:0-0(2004).
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DR EMBL; AY439203; AAS17533.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6T2W7; -.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProt.
DR GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.210; -; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR Pfam; PF01208; URO-D; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 126..220
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 222..268
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT REGION 104..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAS17533.1"
FT NON_TER 268
FT /evidence="ECO:0000313|EMBL:AAS17533.1"
SQ SEQUENCE 268 AA; 28981 MW; 81FABD33015B6FDF CRC64;
GDMYPGMDKA KQAIGGQISL VGTLSPYSTL MHGTTEAVRN EVKKLAAEVG YNGGLIVMPG
CDIDWNIPDG NLHAMIQQCA EIKYPMDIPA LGDLSNVYLA GHPKHPGKRS SSVAGDTQVA
ELKTRHEDLT PVEEVNEKLV EAIMEYDGDK AIEWTKKGLE RGMTPQAIVF DGLSLGMKIV
GDLYERNERF VTDMLKAAKT MDKAMPILTP LLEANGGGDG PTGTVVVGLV RGNTQDIGKN
LVCLMLKANG FKVIDKGKNV KPEQFIER
//
