ID Q6WEE6_TAUBU Unreviewed; 84 AA.
AC Q6WEE6;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Neurotrophin-6/7 {ECO:0000313|EMBL:AAQ63408.1};
DE Flags: Fragment;
GN Name=NT-6/7 {ECO:0000313|EMBL:AAQ63408.1};
OS Taurulus bubalis (Long-spined sea scorpion) (Cottus bubalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Cottales; Cottidae; Taurulus.
OX NCBI_TaxID=61643 {ECO:0000313|EMBL:AAQ63408.1};
RN [1] {ECO:0000313|EMBL:AAQ63408.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=14572460; DOI=10.1016/S1044-7431(03)00195-7;
RA Dethleffsen K., Heinrich G., Lauth M., Knapik E.W., Meyer M.;
RT "Insert-containing neurotrophins in teleost fish and their relationship to
RT nerve growth factor.";
RL Mol. Cell. Neurosci. 24:380-394(2003).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the NGF-beta family.
CC {ECO:0000256|ARBA:ARBA00010783}.
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DR EMBL; AY293566; AAQ63408.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6WEE6; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR020408; Nerve_growth_factor-like.
DR InterPro; IPR002072; Nerve_growth_factor-rel.
DR PANTHER; PTHR11589:SF10; BETA-NERVE GROWTH FACTOR; 1.
DR PANTHER; PTHR11589; NERVE GROWTH FACTOR NGF -RELATED; 1.
DR Pfam; PF00243; NGF; 1.
DR SMART; SM00140; NGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS50270; NGF_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1..84
FT /note="Nerve growth factor-related"
FT /evidence="ECO:0000259|SMART:SM00140"
FT REGION 42..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAQ63408.1"
FT NON_TER 84
FT /evidence="ECO:0000313|EMBL:AAQ63408.1"
SQ SEQUENCE 84 AA; 8704 MW; C5AAFAB784D65EAF CRC64;
SINTWVGNLT RATDIAGNEV RVLPNVTINN VVKKQFFYET TCRSPTHRGS GTANGGKPGG
KPGGRGGKQG SRSGTSGCLG IDSR
//
