ID GPR34_GORGO Reviewed; 381 AA.
AC Q6XCF2;
DT 13-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 29-MAY-2013, entry version 47.
DE RecName: Full=Probable G-protein coupled receptor 34;
GN Name=GPR34;
OS Gorilla gorilla gorilla (Lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Gorilla.
OX NCBI_TaxID=9595;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=12835326; DOI=10.1074/jbc.M303346200;
RA Schulz A., Schoneberg T.;
RT "The structural evolution of a P2Y-like G-protein-coupled receptor.";
RL J. Biol. Chem. 278:35531-35541(2003).
CC -!- FUNCTION: Orphan receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC (By similarity).
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
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DR EMBL; AY241078; AAP04287.1; -; Genomic_DNA.
DR ProteinModelPortal; Q6XCF2; -.
DR HOVERGEN; HBG063715; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR002286; purinergic_P2Y_rcpt.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01157; P2YPURNOCPTR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Complete proteome; Disulfide bond;
KW G-protein coupled receptor; Glycoprotein; Membrane; Receptor;
KW Reference proteome; Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1 381 Probable G-protein coupled receptor 34.
FT /FTId=PRO_0000069558.
FT TOPO_DOM 1 61 Extracellular (Potential).
FT TRANSMEM 62 82 Helical; Name=1; (Potential).
FT TOPO_DOM 83 88 Cytoplasmic (Potential).
FT TRANSMEM 89 109 Helical; Name=2; (Potential).
FT TOPO_DOM 110 128 Extracellular (Potential).
FT TRANSMEM 129 149 Helical; Name=3; (Potential).
FT TOPO_DOM 150 171 Cytoplasmic (Potential).
FT TRANSMEM 172 192 Helical; Name=4; (Potential).
FT TOPO_DOM 193 216 Extracellular (Potential).
FT TRANSMEM 217 237 Helical; Name=5; (Potential).
FT TOPO_DOM 238 269 Cytoplasmic (Potential).
FT TRANSMEM 270 290 Helical; Name=6; (Potential).
FT TOPO_DOM 291 310 Extracellular (Potential).
FT TRANSMEM 311 331 Helical; Name=7; (Potential).
FT TOPO_DOM 332 381 Cytoplasmic (Potential).
FT CARBOHYD 28 28 N-linked (GlcNAc...) (Potential).
FT CARBOHYD 36 36 N-linked (GlcNAc...) (Potential).
FT CARBOHYD 42 42 N-linked (GlcNAc...) (Potential).
FT CARBOHYD 200 200 N-linked (GlcNAc...) (Potential).
FT CARBOHYD 295 295 N-linked (GlcNAc...) (Potential).
FT DISULFID 127 204 By similarity.
SQ SEQUENCE 381 AA; 43860 MW; 491FC016E5624379 CRC64;
MRSHTITMTT TSVSSWPYSS HRMRFITNHS DQPPQNFSAT PNVTTCPMDE KLLSTVLTTS
YSVIFIVGLV GNIIALYVFL GIHRKRNSIQ IYLLNVAIAD LLLIFCLPFR IMYHINQNKW
TLGVILCKVV GTLFYMNMYI SIILLGFISL DRYIKINRSI QQRKAITTKQ SIYVCCIVWM
LALGGFLTMI ILTLKKGGHN STMCFHYRDK HNAKGEAIFN FILVVMFWLI FLLIILSYIK
IGKNLLRISK RRSKFPNSGK YATTARNSFI VLIIFTICFV PYHAFRFIYI SSQLNVSSCY
WKEIVHKTNE IMLVLSSFNS CLDPVMYFLM SSNIRKIMCQ LLFRRFQGEP SRSESTSEFK
PGYSLHDTSV AVKIQSSSKS T
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