ID Q6XDE6_9GAMM Unreviewed; 321 AA.
AC Q6XDE6;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:AAP69921.1};
OS Aeromonas sp. P1W-98.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=234695 {ECO:0000313|EMBL:AAP69921.1};
RN [1] {ECO:0000313|EMBL:AAP69921.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P1W-98 {ECO:0000313|EMBL:AAP69921.1};
RX PubMed=15388703; DOI=10.1099/ijs.0.03048-0;
RA Soler L., Yanez M.A., Chacon M.R., Aguilera-Arreola M.G., Catalan V.,
RA Figueras M.J., Martinez-Murcia A.J.;
RT "Phylogenetic analysis of the genus Aeromonas based on two housekeeping
RT genes.";
RL Int. J. Syst. Evol. Microbiol. 54:1511-1519(2004).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; AY237563; AAP69921.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6XDE6; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 283..321
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAP69921.1"
FT NON_TER 321
FT /evidence="ECO:0000313|EMBL:AAP69921.1"
SQ SEQUENCE 321 AA; 35568 MW; 61725D982B9D0B3A CRC64;
RNGHVYEQTY HLGEPHAPLK QIGDSSSGTG TEVRFWPSPT IFTDTLYHYE ILAKRLRELS
FLNSGVSIRL QDERDGREVH FCYEGGIKAF VEYLNQNKTP IHPKVFHFST EQDGIGVEVA
MQWNDAYQEG VYCFTNNIPQ RDGGTHLVGF RTALTRTLNT YMDKEDYSKK AKSAASGDDV
REGLIAVISV KVPDPKFSSQ TKDKLVSSEV KTAVEQAMGE KLGEFLLENP GDAKIVVNKI
IDAARAREAA RKARELTRRK GALDIAGLPG KLADCQEKDP ALSELYIVEG DSAGGSAKQG
RNRKNQAILP LKGKILNVEK A
//
