ID   Q6XVL0_STRCA            Unreviewed;        55 AA.
AC   Q6XVL0;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   24-JAN-2024, entry version 65.
DE   SubName: Full=Preproinsulin {ECO:0000313|EMBL:AAP45972.1};
DE   Flags: Fragment;
OS   Struthio camelus (Common ostrich).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC   Struthio.
OX   NCBI_TaxID=8801 {ECO:0000313|EMBL:AAP45972.1};
RN   [1] {ECO:0000313|EMBL:AAP45972.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15012953; DOI=10.1016/S1055-7903(03)00254-9;
RA   Simon J., Laurent S., Grolleau G., Thoraval P., Soubieux D., Rasschaert D.;
RT   "Evolution of preproinsulin gene in birds.";
RL   Mol. Phylogenet. Evol. 30:755-766(2004).
RN   [2] {ECO:0000313|EMBL:AAP45972.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Simon J., Laurent S., Grolleau G., Thoraval P., Soubieux D., Rasschaert D.;
RT   "Erratum to 'Evolution of preproinsulin gene in birds'.";
RL   Mol. Phylogenet. Evol. 31:807-809(2004).
CC   -!- FUNCTION: Insulin decreases blood glucose concentration. It increases
CC       cell permeability to monosaccharides, amino acids and fatty acids. It
CC       accelerates glycolysis, the pentose phosphate cycle, and glycogen
CC       synthesis in liver. {ECO:0000256|ARBA:ARBA00002985}.
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DR   EMBL; AY206828; AAP45972.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6XVL0; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   CDD; cd04367; IlGF_insulin_like; 1.
DR   Gene3D; 1.10.100.10; Insulin-like; 1.
DR   InterPro; IPR004825; Insulin.
DR   InterPro; IPR016179; Insulin-like.
DR   InterPro; IPR036438; Insulin-like_sf.
DR   PANTHER; PTHR11454:SF9; INSULIN; 1.
DR   PANTHER; PTHR11454; INSULIN/INSULIN GROWTH FACTOR; 1.
DR   Pfam; PF00049; Insulin; 1.
DR   PRINTS; PR00277; INSULIN.
DR   SMART; SM00078; IlGF; 1.
DR   SUPFAM; SSF56994; Insulin-like; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..55
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004282221"
FT   DOMAIN          21..53
FT                   /note="Insulin-like"
FT                   /evidence="ECO:0000259|SMART:SM00078"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAP45972.1"
FT   NON_TER         55
FT                   /evidence="ECO:0000313|EMBL:AAP45972.1"
SQ   SEQUENCE   55 AA;  5931 MW;  38E3954535137FD6 CRC64;
     LPLLVLLALS GPGTSHAAAN QHLCGSHLVE ALYLVCGERG FFYSPKARRD IEQPL
//