ID   Q705N7_ARATH            Unreviewed;       390 AA.
AC   Q705N7;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Chalcone synthase {ECO:0000313|EMBL:CAF04432.1};
DE   Flags: Fragment;
GN   Name=chs {ECO:0000313|EMBL:CAF04432.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000313|EMBL:CAF04432.1};
RN   [1] {ECO:0000313|EMBL:CAF04432.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Ramos-Onsins S.E., Stranger B.E., Mitchell-Olds T., Aguade M.;
RT   "Multilocus analysis of variation and speciation in the closely-related
RT   species Arabidopsis halleri and A. lyrata.";
RL   Genetics 16:373-388(2003).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC       ECO:0000256|RuleBase:RU003633}.
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DR   EMBL; AJ619910; CAF04432.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q705N7; -.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877:SF14; CHALCONE SYNTHASE; 1.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW   Transferase {ECO:0000256|RuleBase:RU003633}.
FT   DOMAIN          10..232
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          243..390
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        168
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
FT   NON_TER         390
FT                   /evidence="ECO:0000313|EMBL:CAF04432.1"
SQ   SEQUENCE   390 AA;  42590 MW;  078CFFE03A1A8F13 CRC64;
     MVMAGASSMD EIRQAQRADG PAGILAIGTA NPENHVLQAE YPDYYFRITN SEHMTDLKEK
     FKRSDKSTIR KRHMHLTEEF LKENPHMCAY MAPSLDTRQD IVVVEVPKLG KEAAVKAIKE
     WGQPKSKITH VVFCTTSGVD MPGADYQLTK LLGLRPSVKR LMMYQQGCFA GGTVLRIAKD
     LAENNRGARV LVVCSEITAV TFRGPSDTHL DSLVGQALFS DGAAALIVGS DPDTSVGEKP
     IFEMVSAAQT ILPDSDGAID GHLREVGLTF HLLKDVPGLI SKNIVKSLDE AFKPLGISDW
     NSLFWIAHPG GPAILDQVEI KLGLKEEKMR ATRHVLSEYG NMSSACVLFI LDEMRRKSAK
     DGVATTGEGL EWGVLFGFGP GLTVETVVLH
//