ID Q70DZ1_ENTFL Unreviewed; 472 AA.
AC Q70DZ1;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Tetracycline resistance protein TetM {ECO:0000313|EMBL:CAE51930.1};
DE Flags: Fragment;
GN Name=tetM {ECO:0000313|EMBL:CAE51930.1};
OS Enterococcus faecalis (Streptococcus faecalis).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1351 {ECO:0000313|EMBL:CAE51930.1};
RN [1] {ECO:0000313|EMBL:CAE51930.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JH2-2 {ECO:0000313|EMBL:CAE51930.1};
RX PubMed=15006778; DOI=10.1128/AEM.70.3.1555-1562.2004;
RA Huys G., D'Haene K., Collard J.M., Swings J.;
RT "Prevalence and molecular characterization of tetracycline resistance in
RT Enterococcus isolates from food.";
RL Appl. Environ. Microbiol. 70:1555-1562(2004).
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DR EMBL; AJ585076; CAE51930.1; -; Genomic_DNA.
DR AlphaFoldDB; Q70DZ1; -.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
DR CDD; cd03690; Tet_II; 1.
DR CDD; cd16258; Tet_III; 1.
DR CDD; cd01684; Tet_like_IV; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF1; RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR01037; TCRTETOQM.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cyclin {ECO:0000313|EMBL:CAE51930.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 1..150
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAE51930.1"
FT NON_TER 472
FT /evidence="ECO:0000313|EMBL:CAE51930.1"
SQ SEQUENCE 472 AA; 53793 MW; 03ED754B49DA2A6D CRC64;
HGAILLISAK DGVQAQTRIL FHALRKMGIP TIFFINKIDQ NGIDLSTVYQ DIKEKLSAEI
VIKQKVELYP NVCVTNFTES EQWDTVIEGN DDLLEKYMSG KSLEALELEQ EESIRFQNCS
LFPLYHGSAK SNIGIDNLIE VITNKFYSST HRGPSELCGN VFKIEYTKKR QRLAYIRLYS
GVLHLRDSVR VSEKEKIKVT EMYTSINGEL CKIDRAYSGE IVILQNEFLK LNSVLGDTKL
LPQRKKIENP HPLLQTTVEP SKPEQREMLL DALLEISDSD PLLRYYVDST THEIILSFLG
KVQMEVISAL LQEKYHVEIE LKEPTVIYME RPLKNAEYTI HIEVPPNPFW ASIGLSVSPL
PLGSGMQYES SVSLGYLNQS FQNAVMEGIR YGCEQGLYGW NVTDCKICFK YGLYYSPVST
PADFRMLAPI VLEQVLKKAG TELLEPYLSF KIYAPQEYLS RAYNDAPKYC AN
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