ID Q72L02_THET2 Unreviewed; 355 AA.
AC Q72L02;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=Hypothetical conserved protein {ECO:0000313|EMBL:AAS80611.1};
GN OrderedLocusNames=TT_C0263 {ECO:0000313|EMBL:AAS80611.1};
OS Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=262724 {ECO:0000313|EMBL:AAS80611.1, ECO:0000313|Proteomes:UP000000592};
RN [1] {ECO:0000313|EMBL:AAS80611.1, ECO:0000313|Proteomes:UP000000592}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-163 / DSM 7039 / HB27
RC {ECO:0000313|Proteomes:UP000000592};
RX PubMed=15064768; DOI=10.1038/nbt956;
RA Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H.,
RA Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C.,
RA Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P.,
RA Overbeek R., Kramer W., Merkl R., Gottschalk G., Fritz H.-J.;
RT "The genome sequence of the extreme thermophile Thermus thermophilus.";
RL Nat. Biotechnol. 22:547-553(2004).
RN [2] {ECO:0007829|PDB:2PL2}
RP X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 26-230.
RX PubMed=17846496;
RA Lim H., Kim K., Han D., Oh J., Kim Y.;
RT "Crystal structure of TTC0263, a thermophilic TPR protein from Thermus
RT thermophilus HB27.";
RL Mol. Cells 24:27-36(2007).
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DR EMBL; AE017221; AAS80611.1; -; Genomic_DNA.
DR RefSeq; WP_011172714.1; NZ_CP133179.1.
DR PDB; 2PL2; X-ray; 2.50 A; A/B=26-230.
DR PDBsum; 2PL2; -.
DR AlphaFoldDB; Q72L02; -.
DR SMR; Q72L02; -.
DR KEGG; tth:TT_C0263; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG1729; Bacteria.
DR HOGENOM; CLU_042260_0_0_0; -.
DR OrthoDB; 29685at2; -.
DR EvolutionaryTrace; Q72L02; -.
DR Proteomes; UP000000592; Chromosome.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44858; TETRATRICOPEPTIDE REPEAT PROTEIN 6; 1.
DR PANTHER; PTHR44858:SF1; UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF14559; TPR_19; 2.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 4.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:2PL2}; Signal {ECO:0000256|SAM:SignalP};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..355
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004284033"
FT REPEAT 29..62
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 175..208
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 243..276
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 278..311
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 355 AA; 39486 MW; 30C1D3F0F8966C31 CRC64;
MRWLLVVAGL LAAGGLAQTP PPPAAQTAEQ NPLRLGVQLY ALGRYDAALT LFERALKENP
QDPEALYWLA RTQLKLGLVN PALENGKTLV ARTPRYLGGY MVLSEAYVAL YRQAEDRERG
KGYLEQALSV LKDAERVNPR YAPLHLQRGL VYALLGERDK AEASLKQALA LEDTPEIRSA
LAELYLSMGR LDEALAQYAK ALEQAPKDLD LRVRYASALL LKGKAEEAAR VLEEGHRIKP
LNAEGWYTLG QAYLALGRTK EAGVALENAV ALAPLRFPAA YYYLGQVYLA LGDYPKAKSR
LTVAVRLEPK RAEYRYSLCL ANEKLGDKEG ARYQCQEALK LKPDYKEAEE VLKRL
//
