ID Q72S24_LEPIC Unreviewed; 394 AA.
AC Q72S24;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=HD-GYP domain-containing protein {ECO:0000259|PROSITE:PS51832};
GN OrderedLocusNames=LIC_11563 {ECO:0000313|EMBL:AAS70159.1};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni
OS (strain Fiocruz L1-130).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=267671 {ECO:0000313|EMBL:AAS70159.1, ECO:0000313|Proteomes:UP000007037};
RN [1] {ECO:0000313|EMBL:AAS70159.1, ECO:0000313|Proteomes:UP000007037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fiocruz L1-130 {ECO:0000313|EMBL:AAS70159.1,
RC ECO:0000313|Proteomes:UP000007037};
RX PubMed=15028702; DOI=10.1128/JB.186.7.2164-2172.2004;
RA Nascimento A.L., Ko A.I., Martins E.A., Monteiro-Vitorello C.B., Ho P.L.,
RA Haake D.A., Verjovski-Almeida S., Hartskeerl R.A., Marques M.V.,
RA Oliveira M.C., Menck C.F., Leite L.C., Carrer H., Coutinho L.L.,
RA Degrave W.M., Dellagostin O.A., El-Dorry H., Ferro E.S., Ferro M.I.,
RA Furlan L.R., Gamberini M., Giglioti E.A., Goes-Neto A., Goldman G.H.,
RA Goldman M.H., Harakava R., Jeronimo S.M., Junqueira-De-Azevedo I.L.,
RA Kimura E.T., Kuramae E.E., Lemos E.G., Lemos M.V., Marino C.L., Nunes L.R.,
RA De Oliveira R.C., Pereira G.G., Reis M.S., Schriefer A., Siqueira W.J.,
RA Sommer P., Tsai S.M., Simpson A.J., Ferro J.A., Camargo L.E.,
RA Kitajima J.P., Setubal J.C., Van Sluys M.A.;
RT "Comparative genomics of two Leptospira interrogans serovars reveals novel
RT insights into physiology and pathogenesis.";
RL J. Bacteriol. 186:2164-2172(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE016823; AAS70159.1; -; Genomic_DNA.
DR RefSeq; WP_000712870.1; NC_005823.1.
DR AlphaFoldDB; Q72S24; -.
DR GeneID; 61144862; -.
DR KEGG; lic:LIC_11563; -.
DR HOGENOM; CLU_000445_92_1_12; -.
DR Proteomes; UP000007037; Chromosome I.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
FT DOMAIN 140..336
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 394 AA; 44955 MW; 6E46190F47291998 CRC64;
MKKFAVSELK PGMRFSKPVY LDKENLFITS NTPVTDSDLD RLNRFGIQEV MTAGELLQLE
SQYDPNVLET SLDDMIVNTV VDDELQPLKA VYDNLNRIKI TFGNLFREST QIIQDVFKKT
MDEKPLEVTP VREIAERLTD FVRSNQNISY LILANNPPGY YLYNQIANST FYSLILGKLL
EYSRPKMIDL GISCLLADIG MSKVPAVISE KNEQLTDEEF KTIMKHTILG YQILSQKMKL
KNNLAIVALQ HHERYDGNGY PQKLAGNAIE EQARIYSISD NFSALVTNRP HRKKILPHEA
IKSMISMDVG KFDLKLVRTL LNHLSLYPVG SCIELSDKRI GVVLGPNLDK PIRPFIRIIK
DEYGKMVRNL ILVDLLKETN LFISRPVDLQ EISA
//
