ID Q73L72_TREDE Unreviewed; 463 AA.
AC Q73L72;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Aspartate ammonia-lyase, putative {ECO:0000313|EMBL:AAS12507.1};
GN OrderedLocusNames=TDE_1993 {ECO:0000313|EMBL:AAS12507.1};
OS Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153
OS / KCTC 15104).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=243275 {ECO:0000313|EMBL:AAS12507.1, ECO:0000313|Proteomes:UP000008212};
RN [1] {ECO:0000313|EMBL:AAS12507.1, ECO:0000313|Proteomes:UP000008212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104
RC {ECO:0000313|Proteomes:UP000008212};
RX PubMed=15064399; DOI=10.1073/pnas.0307639101;
RA Seshadri R., Myers G.S., Tettelin H., Eisen J.A., Heidelberg J.F.,
RA Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J.,
RA Ren Q., Brinkac L.M., Madupu R., Kolonay J., Durkin S.A., Daugherty S.C.,
RA Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J.,
RA Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S.,
RA Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E., Baca E.,
RA Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T.;
RT "Comparison of the genome of the oral pathogen Treponema denticola with
RT other spirochete genomes.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
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DR EMBL; AE017226; AAS12507.1; -; Genomic_DNA.
DR RefSeq; NP_972596.1; NC_002967.9.
DR RefSeq; WP_002679739.1; NC_002967.9.
DR AlphaFoldDB; Q73L72; -.
DR STRING; 243275.TDE_1993; -.
DR PaxDb; 243275-TDE_1993; -.
DR GeneID; 2740446; -.
DR KEGG; tde:TDE_1993; -.
DR PATRIC; fig|243275.7.peg.1882; -.
DR eggNOG; COG1027; Bacteria.
DR HOGENOM; CLU_021594_4_1_12; -.
DR OrthoDB; 9802809at2; -.
DR Proteomes; UP000008212; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR CDD; cd01357; Aspartase; 1.
DR Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR018951; Fumarase_C_C.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR000362; Fumarate_lyase_fam.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR PANTHER; PTHR42696; ASPARTATE AMMONIA-LYASE; 1.
DR PANTHER; PTHR42696:SF2; ASPARTATE AMMONIA-LYASE; 1.
DR Pfam; PF10415; FumaraseC_C; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:AAS12507.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008212}.
FT DOMAIN 9..340
FT /note="Fumarate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00206"
FT DOMAIN 406..459
FT /note="Fumarase C C-terminal"
FT /evidence="ECO:0000259|Pfam:PF10415"
SQ SEQUENCE 463 AA; 50783 MW; 6A17E234DB99FD7B CRC64;
MRREHDLLGE LDIPEDAYYG IQTFRSVENF QITGLRLCDF PDFIKGLAYT KQAAAEANHE
LGYLSDEVYK AMIQACKEVA EGKFDKEFVV DMIQGGAGTS TNMNANEVIA NRANEILGKA
KGTYSPCHPN NHVNFAQSTN DAYPTAAKLG ISLNTPALID ELKSLVASFR KKAQELGENI
KMGRTQLQDA VPMTLGQEFE SYAASLENEI PQIQFARENL HTINMGATAI GTGINSDPNY
TPKVTSHLAK ISGLDLKAAK NMIAATNDTS DFVTYSSQLK RLSAKLSKIC SDLRLLSSGP
RTGLYDISLP PMQPGSSIMP GKVNPVIPEV VNQVCYRVIG NDTAVILAAE SGQLELNVFE
PVIIYSIFES IKLLINAMKT LRERCVTGIV GNYEHCKESV HRSIGLVTAL NPVIGYEASS
DIAKTALRDN RSVYDLVLER GLLSKEKLDE VLKPENMTKP RKL
//
