ID Q73N95_TREDE Unreviewed; 522 AA.
AC Q73N95;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Cholinephosphate cytidylyltransferase/choline kinase {ECO:0000313|EMBL:AAS11778.1};
GN OrderedLocusNames=TDE_1260 {ECO:0000313|EMBL:AAS11778.1};
OS Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153
OS / KCTC 15104).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=243275 {ECO:0000313|EMBL:AAS11778.1, ECO:0000313|Proteomes:UP000008212};
RN [1] {ECO:0000313|EMBL:AAS11778.1, ECO:0000313|Proteomes:UP000008212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104
RC {ECO:0000313|Proteomes:UP000008212};
RX PubMed=15064399; DOI=10.1073/pnas.0307639101;
RA Seshadri R., Myers G.S., Tettelin H., Eisen J.A., Heidelberg J.F.,
RA Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J.,
RA Ren Q., Brinkac L.M., Madupu R., Kolonay J., Durkin S.A., Daugherty S.C.,
RA Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J.,
RA Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S.,
RA Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E., Baca E.,
RA Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T.;
RT "Comparison of the genome of the oral pathogen Treponema denticola with
RT other spirochete genomes.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
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DR EMBL; AE017226; AAS11778.1; -; Genomic_DNA.
DR RefSeq; NP_971867.1; NC_002967.9.
DR AlphaFoldDB; Q73N95; -.
DR STRING; 243275.TDE_1260; -.
DR PaxDb; 243275-TDE_1260; -.
DR KEGG; tde:TDE_1260; -.
DR PATRIC; fig|243275.7.peg.1212; -.
DR eggNOG; COG0510; Bacteria.
DR eggNOG; COG4750; Bacteria.
DR HOGENOM; CLU_467630_0_0_12; -.
DR OrthoDB; 9803871at2; -.
DR Proteomes; UP000008212; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05151; ChoK-like; 1.
DR CDD; cd02523; PC_cytidylyltransferase; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR017190; Bifunc_CCT/choline_kinase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43584; NUCLEOTIDYL TRANSFERASE; 1.
DR PANTHER; PTHR43584:SF5; PROTEIN LICC; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR PIRSF; PIRSF037383; LicCA; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AAS11778.1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:AAS11778.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008212};
KW Transferase {ECO:0000313|EMBL:AAS11778.1}.
FT DOMAIN 4..110
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 522 AA; 61616 MW; 725C6DC402D21D26 CRC64;
MDNAIIMAAG FGSRFVPLTY ATPKGLLEVF GERMIERQIE QLKAAGIDDI TIVVGYLKET
FEYLIDKYGV KFVYNPDFKN KNNLSTLYHV RDELKSTYIL SSDNWLRENM YHSHEYDSWY
SSVKVAGKTK EWILKLGLHD KIMDVKVGGR NGWVMYGPVY FSKEFSDKIR PLIEEAYERD
DTDDWYWEDV YMRNIKELTM FANKQGDHQV YEFESLDEIR LFDSSYLISS HDKWLELISD
VFKRPEHSIT NLKPLKFGMT NKSFLFEFEG EEYIFRIPGE GTEALINRKE EYEVYKAISP
LNLSDSIIYF DPEKGVKITK FIPNSHTADA RNPEDLKKCM KVARRLHESG LKVAHSFDLR
ERINYYEKIA NEKNGIFYHD YHEVRLLMNE LLELIENTEK PHVLCHIDLV PDNFIINGND
VHLIDWEYAA MCDPLIDIAM FAIYAHYDNE ELENLMSFYF ERPVKEEERM RIYCYVALSG
FLWALWTCYK EALGVSFGDY GLKMYRYAKD YYKKIKELGG NL
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