ID Q749I2_GEOSL Unreviewed; 517 AA.
AC Q749I2;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Glycerol-3-phosphate dehydrogenase, FAD-dependent {ECO:0000313|EMBL:AAR36155.1};
GN Name=glpA {ECO:0000313|EMBL:AAR36155.1};
GN OrderedLocusNames=GSU2761 {ECO:0000313|EMBL:AAR36155.1};
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR36155.1, ECO:0000313|Proteomes:UP000000577};
RN [1] {ECO:0000313|EMBL:AAR36155.1, ECO:0000313|Proteomes:UP000000577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA
RC {ECO:0000313|Proteomes:UP000000577};
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-dependent glycerol-3-phosphate
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00007330}.
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DR EMBL; AE017180; AAR36155.1; -; Genomic_DNA.
DR RefSeq; NP_953805.1; NC_002939.5.
DR RefSeq; WP_010943389.1; NC_002939.5.
DR AlphaFoldDB; Q749I2; -.
DR SMR; Q749I2; -.
DR STRING; 243231.GSU2761; -.
DR EnsemblBacteria; AAR36155; AAR36155; GSU2761.
DR KEGG; gsu:GSU2761; -.
DR PATRIC; fig|243231.5.peg.2785; -.
DR eggNOG; COG0578; Bacteria.
DR HOGENOM; CLU_015740_4_1_7; -.
DR InParanoid; Q749I2; -.
DR OrthoDB; 9766796at2; -.
DR Proteomes; UP000000577; Chromosome.
DR GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
DR GO; GO:0004368; F:glycerol-3-phosphate dehydrogenase (quinone) activity; IBA:GO_Central.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IBA:GO_Central.
DR Gene3D; 1.10.8.870; Alpha-glycerophosphate oxidase, cap domain; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR031656; DAO_C.
DR InterPro; IPR038299; DAO_C_sf.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000447; G3P_DH_FAD-dep.
DR PANTHER; PTHR11985; GLYCEROL-3-PHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11985:SF15; GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16901; DAO_C; 1.
DR PRINTS; PR01001; FADG3PDH.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000577}.
FT DOMAIN 17..373
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 384..497
FT /note="Alpha-glycerophosphate oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16901"
SQ SEQUENCE 517 AA; 55885 MW; 49ACE2E7312D5141 CRC64;
MKREDLLRHL AETEVWDMIV IGGGATGLGT AVEAAGRGYR TLLLEQGDFA QGTSSRSTKL
IHGGVRYLQQ GNLTLVLEAL RERGLLIRNA PHLVHNLSFV VPLYDWWEGP FYGIGLKLYD
VLAGKLGLGP SRLLSREETL GHIPTVEPHG LRGGVIYHDG QFDDSRLAIS LALTLADLGG
VALNHFPVTG IISRDGLVAG VEARDRETGG AFRIMGRAVI NAAGPFVDGV RRLADPAARD
LIAPSQGVHL VLDGSFLPGD SAIMVPHTDD GRVLFAVPWH GRTVVGTTDT PIPAAGLEPR
PLPEEIDFLL SHAARYLTRH PERRDVLSTF AGIRPLVRSD SGGDTASLSR DHTLLVEGSG
LVTIAGGKWT TYRKMGEDTV TAAAQVAGLD HRPSVTETLR IHGWQEDATE GPLQVYGSDA
AALEQLLREN AAWREPLHPA LPYCAGEVVW GVRHEWARTV EDVLARRTRA LLLDARAAVA
AAPRVAELMA RELGRDSDWQ AAQVAAFTHL ARGYLPE
//
