ID Q74BV5_GEOSL Unreviewed; 708 AA.
AC Q74BV5;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 2.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Response receiver sensor diguanylate cyclase/phosphodiesterase, PAS domain-containing {ECO:0000313|EMBL:AAR35303.2};
GN OrderedLocusNames=GSU1927 {ECO:0000313|EMBL:AAR35303.2};
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR35303.2, ECO:0000313|Proteomes:UP000000577};
RN [1] {ECO:0000313|EMBL:AAR35303.2, ECO:0000313|Proteomes:UP000000577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA
RC {ECO:0000313|Proteomes:UP000000577};
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
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DR EMBL; AE017180; AAR35303.2; -; Genomic_DNA.
DR RefSeq; NP_952976.2; NC_002939.5.
DR RefSeq; WP_010942572.1; NC_002939.5.
DR AlphaFoldDB; Q74BV5; -.
DR SMR; Q74BV5; -.
DR STRING; 243231.GSU1927; -.
DR EnsemblBacteria; AAR35303; AAR35303; GSU1927.
DR KEGG; gsu:GSU1927; -.
DR PATRIC; fig|243231.5.peg.1965; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_50_7; -.
DR InParanoid; Q74BV5; -.
DR OrthoDB; 9777298at2; -.
DR Proteomes; UP000000577; Chromosome.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000000577}.
FT DOMAIN 12..128
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 215..267
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 299..444
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 453..707
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT MOD_RES 61
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 708 AA; 79107 MW; B0C5D3DE144EE64E CRC64;
MRKEGKDGAS ATVMIIDDDE LVRVLARRAV EQGGFAVIEA GDGVTAIEMF SRLVPDIILL
DVVMPGMGGF DVCRRIRRLP GGDRVQILVM TSLDDTGAID EAYEAGASDF LAKPIDWVLL
PRRIRYLLRA KLAFDELHKS RTMLYNAQRI ARLGNWEFDL ETNVFTCSEE SCRIFGIRDH
RQGKSHRALM RRVHPEDRVT VKKAIFQAFR TGVGYCMDHR IVLDDGVERI VSQHAELLSA
DDGRTSRLVG TVHDITERTL AEERIRYLAH HDTLTALPNR FQFEERMEQA LAFAQRNGFM
MAVLFLDLDH FKKVNDTLGH HAGDRLLQEA AGRLMKCLRR SDTLTHASRE DASPFISRMG
GDEFTILLTD LAHPQDAARV SQRIITALSK RYVIGGHEVF VGASIGISLF PSDGEDCDQL
LRNADTAMYH AKELGRNTYQ YYSGSMNAMA LERLTLENNL RWALKRNEFR LCYQPQLDAA
SGRVVGMEAL LSWHRPGCDV VPPDDFIPLA EETGLIASIG EWVLWNACAQ AVTWLHEGLP
PVRVAVNLSS LQFRSRRLAE LVRKVLRATG LPPSHLELEI TEGVFMSNEE DAAVVIRDLK
KMGVRFSVDD FGTGYSSLSR LSRFPLDALK IDRSFVRDIS ADPAAAGLTA AIIAMARNLG
LNVIAEGVET HEQFAFLRAN GCAEVQGFLF SQPLNPDAAA AFLRARSR
//
