ID Q74DL9_GEOSL Unreviewed; 361 AA.
AC Q74DL9; Q749Z4;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Transposase of ISGsu2, IS5 family {ECO:0000313|EMBL:AAR34673.1};
GN OrderedLocusNames=GSU0559 {ECO:0000313|EMBL:AAR33890.1}, GSU1297
GN {ECO:0000313|EMBL:AAR34673.1}, GSU2597 {ECO:0000313|EMBL:AAR35970.1};
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR34673.1, ECO:0000313|Proteomes:UP000000577};
RN [1] {ECO:0000313|EMBL:AAR34673.1, ECO:0000313|Proteomes:UP000000577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA
RC {ECO:0000313|Proteomes:UP000000577}, and PCA
RC {ECO:0000313|EMBL:AAR34673.1};
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
RN [2] {ECO:0000313|EMBL:AAR34673.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PCA {ECO:0000313|EMBL:AAR34673.1};
RA Methe B., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA Weidman J.M., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA Lovley D.R., Fraser C.M.;
RL Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAR34673.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PCA {ECO:0000313|EMBL:AAR34673.1};
RX PubMed=22967216; DOI=10.1186/1471-2164-13-471;
RA Butler J.E., Young N.D., Aklujkar M., Lovley D.R.;
RT "Comparative genomic analysis of Geobacter sulfurreducens KN400, a strain
RT with enhanced capacity for extracellular electron transfer and electricity
RT production.";
RL BMC Genomics 13:471-471(2012).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence IS5.
CC {ECO:0000256|ARBA:ARBA00003544}.
CC -!- SIMILARITY: Belongs to the transposase 11 family.
CC {ECO:0000256|ARBA:ARBA00010075}.
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DR EMBL; AE017180; AAR33890.1; -; Genomic_DNA.
DR EMBL; AE017180; AAR34673.1; -; Genomic_DNA.
DR EMBL; AE017180; AAR35970.1; -; Genomic_DNA.
DR RefSeq; NP_951617.1; NC_002939.5.
DR RefSeq; NP_952350.1; NC_002939.5.
DR RefSeq; NP_953643.1; NC_002939.5.
DR RefSeq; WP_010941225.1; NC_002939.5.
DR AlphaFoldDB; Q74DL9; -.
DR EnsemblBacteria; AAR33890; AAR33890; GSU0559.
DR EnsemblBacteria; AAR34673; AAR34673; GSU1297.
DR EnsemblBacteria; AAR35970; AAR35970; GSU2597.
DR KEGG; gsu:GSU0559; -.
DR KEGG; gsu:GSU1297; -.
DR KEGG; gsu:GSU2597; -.
DR PATRIC; fig|243231.5.peg.1293; -.
DR eggNOG; COG3039; Bacteria.
DR HOGENOM; CLU_021293_3_2_7; -.
DR OrthoDB; 5526284at2; -.
DR Proteomes; UP000000577; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR InterPro; IPR047959; Transpos_IS5.
DR InterPro; IPR002559; Transposase_11.
DR InterPro; IPR008490; Transposase_InsH_N.
DR NCBIfam; NF033581; transpos_IS5_4; 1.
DR PANTHER; PTHR35604; TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED; 1.
DR PANTHER; PTHR35604:SF2; TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED; 1.
DR Pfam; PF01609; DDE_Tnp_1; 1.
DR Pfam; PF05598; DUF772; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464};
KW Transposition {ECO:0000256|ARBA:ARBA00022578}.
FT DOMAIN 53..125
FT /note="Transposase InsH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05598"
FT DOMAIN 199..350
FT /note="Transposase IS4-like"
FT /evidence="ECO:0000259|Pfam:PF01609"
FT REGION 161..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 361 AA; 40784 MW; 06648E7484FDDB83 CRC64;
MRGFDSNTEA LFTYVTPESF VPKDHPLRAI RKMADEALAG MDKLFDSMYA TTGRSSIPPE
KLLKAQLLMI LYSIRSNRQL VEQIHYNFLF RWFLGMGLDE KVWDHSSFTK NSDRLIGSEV
AAEFLSRVLA QAERKRLLSR EHFTVDGTLI EAWASIKSFK PKDGPPSAGG GGRNDTVDFK
GQKLTNETHG STTDPDARLY RKGKNKEAKL CYQGHTLMEN RSGLIIRTKV TTATGCGERD
AAKAMVQQLP RTTRRITLGC DKGYDTESFV KELRRLKITP HVAQNTSNRK SAIDGRTTKH
PNYTISQKIR KRIEEGFGWM KTVGSLRKTM YRGIEKIAMQ LDLHAAAYNL VRMKNLGLGV
T
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