ID   Q74K82_LACJO            Unreviewed;       343 AA.
AC   Q74K82;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 108.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAS08692.1};
GN   OrderedLocusNames=LJ_0871 {ECO:0000313|EMBL:AAS08692.1};
OS   Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=257314 {ECO:0000313|EMBL:AAS08692.1, ECO:0000313|Proteomes:UP000000581};
RN   [1] {ECO:0000313|EMBL:AAS08692.1, ECO:0000313|Proteomes:UP000000581}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CNCM I-1225 / La1 / NCC 533
RC   {ECO:0000313|Proteomes:UP000000581};
RX   PubMed=14983040; DOI=10.1073/pnas.0307327101;
RA   Pridmore R.D., Berger B., Desiere F., Vilanova D., Barretto C.,
RA   Pittet A.-C., Zwahlen M.-C., Rouvet M., Altermann E., Barrangou R.,
RA   Mollet B., Mercenier A., Klaenhammer T., Arigoni F., Schell M.A.;
RT   "The genome sequence of the probiotic intestinal bacterium Lactobacillus
RT   johnsonii NCC 533.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:2512-2517(2004).
CC   -!- SIMILARITY: Belongs to the SorC transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00010466}.
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DR   EMBL; AE017198; AAS08692.1; -; Genomic_DNA.
DR   RefSeq; WP_004897703.1; NC_005362.1.
DR   AlphaFoldDB; Q74K82; -.
DR   GeneID; 83570732; -.
DR   KEGG; ljo:LJ_0871; -.
DR   PATRIC; fig|257314.6.peg.728; -.
DR   eggNOG; COG2390; Bacteria.
DR   HOGENOM; CLU_054506_2_0_9; -.
DR   Proteomes; UP000000581; Chromosome.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1360; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR048715; CggR_N.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR007324; Sugar-bd_dom_put.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR34294:SF5; CENTRAL GLYCOLYTIC GENES REGULATOR; 1.
DR   PANTHER; PTHR34294; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR   Pfam; PF21715; CggR_N; 1.
DR   Pfam; PF04198; Sugar-bind; 1.
DR   SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT   DOMAIN          18..84
FT                   /note="CggR N-terminal DNA binding"
FT                   /evidence="ECO:0000259|Pfam:PF21715"
FT   DOMAIN          90..340
FT                   /note="Sugar-binding"
FT                   /evidence="ECO:0000259|Pfam:PF04198"
SQ   SEQUENCE   343 AA;  37544 MW;  6D3DB0691980C72A CRC64;
     MDSDLTLLQS LVPDVLKIIR QRFLVLEQIS LLAPVGRRVV AKKLGLSERN VRTETDYLRQ
     LGLINIQSYG MELTDKGKRT LKEAAPLIDR LFNASQTEIE LAQKLGIDRA IIVPGDMDRQ
     ERVVDLMGEQ LNSALDLLLP LGKSIITVLG GTTVAGVAHH LSPKLSRYRD LLFVPGRGAV
     GESVEIQSNT VAQMMASETG GKHKGLYLPE NVSSEALTLL LQDTDIANAI SNIYNSDMVI
     HGIGRADVMS KRRGLDVMTS SKLRNDGAVA ECFGYFFDQQ GRLVKRIPRI GLQLEDLDKI
     PHVFAIAAGA SKASAIVAYM HHAPKQTWLI TDEGASNLVL KGK
//