ID Q76DQ7_9PHYC Unreviewed; 596 AA.
AC Q76DQ7;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=glutamine--fructose-6-phosphate transaminase (isomerizing) {ECO:0000256|ARBA:ARBA00012916};
DE EC=2.6.1.16 {ECO:0000256|ARBA:ARBA00012916};
GN Name=k2-gfat {ECO:0000313|EMBL:BAD15299.1};
OS Chlorella virus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Algavirales; Phycodnaviridae; Chlorovirus.
OX NCBI_TaxID=10507 {ECO:0000313|EMBL:BAD15299.1};
RN [1] {ECO:0000313|EMBL:BAD15299.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada T., Sugimoto I., Usami S., Fujie M.;
RT "Introduction and Expression of a CVK2 GFAT gene in Escherichia coli.";
RL Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-
CC phosphate + L-glutamate; Xref=Rhea:RHEA:13237, ChEBI:CHEBI:29985,
CC ChEBI:CHEBI:58359, ChEBI:CHEBI:58725, ChEBI:CHEBI:61527; EC=2.6.1.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001031};
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DR EMBL; AB107976; BAD15299.1; -; Genomic_DNA.
DR SMR; Q76DQ7; -.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; IEA:UniProtKB-EC.
DR GO; GO:1901137; P:carbohydrate derivative biosynthetic process; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR CDD; cd00714; GFAT; 1.
DR CDD; cd05008; SIS_GlmS_GlmD_1; 1.
DR CDD; cd05009; SIS_GlmS_GlmD_2; 1.
DR Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR InterPro; IPR017932; GATase_2_dom.
DR InterPro; IPR005855; GFAT.
DR InterPro; IPR047084; GFAT_N.
DR InterPro; IPR035466; GlmS/AgaS_SIS.
DR InterPro; IPR035490; GlmS/FrlB_SIS.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR NCBIfam; TIGR01135; glmS; 1.
DR PANTHER; PTHR10937; GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING; 1.
DR PANTHER; PTHR10937:SF0; GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING); 1.
DR Pfam; PF13522; GATase_6; 1.
DR Pfam; PF01380; SIS; 2.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51278; GATASE_TYPE_2; 1.
DR PROSITE; PS51464; SIS; 2.
PE 4: Predicted;
KW Aminotransferase {ECO:0000256|ARBA:ARBA00022576};
KW Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:BAD15299.1}.
FT DOMAIN 2..228
FT /note="Glutamine amidotransferase type-2"
FT /evidence="ECO:0000259|PROSITE:PS51278"
FT DOMAIN 283..422
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT DOMAIN 445..586
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 596 AA; 65518 MW; 92FE8E57859B6121 CRC64;
MCGIFGAVSN NNSIEVSIKG IQKLEYRGYD SCGIAYADGD GVIERIRSID GIEDLRKKTL
EESSPVAIAH SRWSTTGIPS VVNAHPHISR GTSGCESRIA VVHNGIIENY QQIRKYLINL
GYTFDSQTDT EVIAHLIDSQ YNGNILHTVQ MAVKHLKGSY AIAVMCHKES GKIVVAKQKS
PLVLGIGSDG AYYIASDVLA LPTNKVVYIS DGFSAELSPG SMTIYDPDGN EVEYEVEDVE
MEQTSMSLDN FDHYMIKEIN EQPISILNTI KNKGFYAEIF GDLAHEIFQK IDNILILACG
TSYHAGLVGK QWIETIARIP VDVHIASEYE PTIPRANTLV ITISQSGETA DTIAALQRAQ
NAGMIYTLCI CNSPKSTLVR ESVMKYITKC GSEVSVASTK AFTSQLVVLY MLANVLANKT
DDLLGDLPQA IERVICLTND EMKRWADEIC TAKSAIFLGR GLNAPVAFEG ALKLKEISYI
HAEGFLGGEL KHGPLALLDD KIPVIVTVAD HAYLDHIKAN IDEVLARNVT VYAIVDQYVN
IEPQERLHVV KVPFVSKEFS PIIHTIPMQL LSYYVAIKLG KNVDKPRNLA KSVTTF
//
