ID Q76KZ1_STRHA Unreviewed; 385 AA.
AC Q76KZ1;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Aminotransferase {ECO:0000313|EMBL:BAD08362.1};
GN Name=vinF {ECO:0000313|EMBL:BAD08362.1};
OS Streptomyces halstedii.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1944 {ECO:0000313|EMBL:BAD08362.1};
RN [1] {ECO:0000313|EMBL:BAD08362.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15112997; DOI=10.1016/S1074-5521(03)00282-5;
RA Ogasawara Y., Katayama K., Minami A., Otsuka M., Eguchi T., Kakinuma K.;
RT "Cloning, sequencing, and functional analysis of the biosynthetic gene
RT cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.";
RL Chem. Biol. 11:79-86(2004).
CC -!- SIMILARITY: Belongs to the DegT/DnrJ/EryC1 family.
CC {ECO:0000256|ARBA:ARBA00037999, ECO:0000256|RuleBase:RU004508}.
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DR EMBL; AB086653; BAD08362.1; -; Genomic_DNA.
DR AlphaFoldDB; Q76KZ1; -.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00616; AHBA_syn; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000653; DegT/StrS_aminotransferase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR30244:SF9; PROTEIN RV3402C; 1.
DR PANTHER; PTHR30244; TRANSAMINASE; 1.
DR Pfam; PF01041; DegT_DnrJ_EryC1; 1.
DR PIRSF; PIRSF000390; PLP_StrS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:BAD08362.1};
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR000390-2};
KW Transferase {ECO:0000313|EMBL:BAD08362.1}.
FT ACT_SITE 191
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000390-1"
FT MOD_RES 191
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR000390-2"
SQ SEQUENCE 385 AA; 41636 MW; 831764A53D7D6EB0 CRC64;
MTDSPVFREP LHVGRPNIGS RARLTERLEG ALDRLYLTNG PLVREFEERL AEVAGVDHCV
AVCNATIGLQ VAAKAAGIRG GDEVIVPAFT WVATAAALDW IGIVPVFCDA DETTGNIDWT
KVEALIGPRT RGIMGVHVFG RPCEVDELEE IAGRHGLPLL FDSAHAIGCT YKGRPVGGFG
TAEVYSFHAT KFVNSFEGGA IVTRDAEFAE RCRELRNFGI TSAGEIRSGG TNAKMNEAAA
AMGLTSLEVM DSLMEANRIN HGRYEKGLDG LPGVWVRGQA EGERANHQYL VIEIDAAVAG
IHRDEVHTAL IAQNVLSRRY FHPSCHQVEP YLSDPARHAP HPLPHAEALA ERVLALPTGT
TVGPSEIDQV CDIIRRCVSA RTPAR
//
