ID Q79ZT8_STRAW Unreviewed; 255 AA.
AC Q79ZT8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Thioesterase {ECO:0000313|EMBL:BAC68117.1};
GN Name=pteH {ECO:0000313|EMBL:BAC68117.1};
GN ORFNames=SAVERM_407 {ECO:0000313|EMBL:BAC68117.1};
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC68117.1, ECO:0000313|Proteomes:UP000000428};
RN [1] {ECO:0000313|EMBL:BAC68117.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN [2] {ECO:0000313|EMBL:BAC68117.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
CC -!- SIMILARITY: Belongs to the thioesterase family.
CC {ECO:0000256|ARBA:ARBA00007169}.
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DR EMBL; BA000030; BAC68117.1; -; Genomic_DNA.
DR RefSeq; WP_010981844.1; NZ_JZJK01000056.1.
DR AlphaFoldDB; Q79ZT8; -.
DR KEGG; sma:SAVERM_407; -.
DR eggNOG; COG3208; Bacteria.
DR HOGENOM; CLU_070456_1_2_11; -.
DR OrthoDB; 8480037at2; -.
DR Proteomes; UP000000428; Chromosome.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR020802; PKS_thioesterase.
DR InterPro; IPR012223; TEII.
DR InterPro; IPR001031; Thioesterase.
DR PANTHER; PTHR11487:SF0; S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN; 1.
DR PANTHER; PTHR11487; THIOESTERASE; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00824; PKS_TE; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT DOMAIN 27..249
FT /note="Polyketide synthase thioesterase"
FT /evidence="ECO:0000259|SMART:SM00824"
SQ SEQUENCE 255 AA; 28425 MW; 5BD5EF53CB825810 CRC64;
MNSPLTEHNS LWIRRFHPRP DSHVRLVCLP HAGGSASFYF PVSRSMPESV DVLCVQYPGR
QDRRTEPLLD SVPALADKVY EALLPWTDRP IALFGHSMGA SLAYEIARRL EQERGITPAT
LIASGRRAPS THRDETVHLR DDDGLVAEMR GLSGTDPQLL GDEDVLRMIL PAIRADYRAA
ETYTWEPGPP LTCPVTCLVG DDDPKVTVEE AAAWSGHTDG PFMLRVFPGG HFFLARHQTE
IVRLMATQLE VLDRP
//
