ID Q7APS6_MYCLE Unreviewed; 310 AA.
AC Q7APS6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Probable LysR family transcriptional regulator {ECO:0000313|EMBL:CAC32195.1};
GN Name=oxyS {ECO:0000313|EMBL:CAC32195.1};
GN OrderedLocusNames=ML2663 {ECO:0000313|EMBL:CAC32195.1};
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631 {ECO:0000313|EMBL:CAC32195.1, ECO:0000313|Proteomes:UP000000806};
RN [1] {ECO:0000313|EMBL:CAC32195.1, ECO:0000313|Proteomes:UP000000806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN {ECO:0000313|EMBL:CAC32195.1,
RC ECO:0000313|Proteomes:UP000000806};
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AL583926; CAC32195.1; -; Genomic_DNA.
DR PIR; E87242; E87242.
DR RefSeq; NP_302698.1; NC_002677.1.
DR RefSeq; WP_010909017.1; NC_002677.1.
DR AlphaFoldDB; Q7APS6; -.
DR STRING; 272631.gene:17576529; -.
DR KEGG; mle:ML2663; -.
DR PATRIC; fig|272631.5.peg.5124; -.
DR Leproma; ML2663; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_2_11; -.
DR OrthoDB; 3181812at2; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd05466; PBP2_LTTR_substrate; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30419; HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD; 1.
DR PANTHER; PTHR30419:SF31; LYSR FAMILY TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000806}.
FT DOMAIN 1..57
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 310 AA; 33722 MW; 80721F9B33E0F146 CRC64;
MLFRQLEYFV AVAQERHFAR AAERCYVSQP ALSSAIAKLE RELNVTLINR GHSFEGLTPE
GERLVVWAKR ILAEHDAFKA EVHAVRSGIT GTLRLGTVPT ASTTASLVLS AFCSEHPLIK
VQICSRLPVT ELHRRLGDFE LDAVIVHSAP DDTHAVDLVP LYHEHYVLVS PADMLPPGAS
VLAWPEASQL PLALLTPDMR DRQLIDRAFA GHAITATPQV ETDSVASLFA QVATGNWACI
VPHTWLWTTP IGAEIRAVEM VDPVLKADVA LATNSAGPGS PVARALVASA KQLALNEFFE
AQLAGITRRR
//
