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Database: UniProt
Entry: Q7CJ93
LinkDB: Q7CJ93
Original site: Q7CJ93 
ID   NUOB_YERPE              Reviewed;         225 AA.
AC   Q7CJ93; Q74T28;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   01-OCT-2014, entry version 66.
DE   RecName: Full=NADH-quinone oxidoreductase subunit B {ECO:0000255|HAMAP-Rule:MF_01356};
DE            EC=1.6.99.5 {ECO:0000255|HAMAP-Rule:MF_01356};
DE   AltName: Full=NADH dehydrogenase I subunit B {ECO:0000255|HAMAP-Rule:MF_01356};
DE   AltName: Full=NDH-1 subunit B {ECO:0000255|HAMAP-Rule:MF_01356};
GN   Name=nuoB {ECO:0000255|HAMAP-Rule:MF_01356};
GN   OrderedLocusNames=YPO2554, y1631, YP_2365;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/JB.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C.,
RA   Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V.,
RA   Straley S.C., McDonough K.A., Nilles M.L., Matson J.S., Blattner F.R.,
RA   Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G.,
RA   Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V.,
RA   Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M.,
RA   Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z.,
RA   Jin L., Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J.,
RA   Yang H., Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-
CC       sulfur (Fe-S) centers, to quinones in the respiratory chain. The
CC       immediate electron acceptor for the enzyme in this species is
CC       believed to be ubiquinone. Couples the redox reaction to proton
CC       translocation (for every two electrons transferred, four hydrogen
CC       ions are translocated across the cytoplasmic membrane), and thus
CC       conserves the redox energy in a proton gradient.
CC       {ECO:0000255|HAMAP-Rule:MF_01356}.
CC   -!- CATALYTIC ACTIVITY: NADH + quinone = NAD(+) + quinol.
CC       {ECO:0000255|HAMAP-Rule:MF_01356}.
CC   -!- COFACTOR: Binds 1 4Fe-4S cluster. {ECO:0000255|HAMAP-
CC       Rule:MF_01356}.
CC   -!- SUBUNIT: NDH-1 is composed of 13 different subunits. Subunits
CC       NuoB, CD, E, F, and G constitute the peripheral sector of the
CC       complex. {ECO:0000255|HAMAP-Rule:MF_01356}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01356}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01356}; Cytoplasmic side {ECO:0000255|HAMAP-
CC       Rule:MF_01356}.
CC   -!- SIMILARITY: Belongs to the complex I 20 kDa subunit family.
CC       {ECO:0000255|HAMAP-Rule:MF_01356}.
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DR   EMBL; AE009952; AAM85200.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS62570.1; -; Genomic_DNA.
DR   EMBL; AL590842; CAL21179.1; -; Genomic_DNA.
DR   PIR; AH0311; AH0311.
DR   RefSeq; NP_668949.1; NC_004088.1.
DR   RefSeq; NP_993693.1; NC_005810.1.
DR   RefSeq; YP_002347515.1; NC_003143.1.
DR   ProteinModelPortal; Q7CJ93; -.
DR   STRING; 214092.YPO2554; -.
DR   PRIDE; Q7CJ93; -.
DR   DNASU; 1146578; -.
DR   EnsemblBacteria; AAM85200; AAM85200; y1631.
DR   EnsemblBacteria; AAS62570; AAS62570; YP_2365.
DR   GeneID; 1146578; -.
DR   GeneID; 1175385; -.
DR   GeneID; 2766086; -.
DR   KEGG; ype:YPO2554; -.
DR   KEGG; ypk:y1631; -.
DR   KEGG; ypm:YP_2365; -.
DR   eggNOG; COG0377; -.
DR   HOGENOM; HOG000228249; -.
DR   KO; K00331; -.
DR   OMA; PRPEAYI; -.
DR   OrthoDB; EOG62K20C; -.
DR   BioCyc; YPES214092:GKDD-2521-MONOMER; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.700; -; 1.
DR   HAMAP; MF_01356; NDH1_NuoB; 1.
DR   InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR   InterPro; IPR006138; NADH_UQ_OxRdtase_20Kd_su.
DR   Pfam; PF01058; Oxidored_q6; 1.
DR   TIGRFAMs; TIGR01957; nuoB_fam; 1.
DR   PROSITE; PS01150; COMPLEX1_20K; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Cell inner membrane; Cell membrane; Complete proteome; Iron;
KW   Iron-sulfur; Membrane; Metal-binding; NAD; Oxidoreductase; Quinone;
KW   Reference proteome; Transport; Ubiquinone.
FT   CHAIN         1    225       NADH-quinone oxidoreductase subunit B.
FT                                /FTId=PRO_0000376410.
FT   METAL        68     68       Iron-sulfur (4Fe-4S). {ECO:0000255|HAMAP-
FT                                Rule:MF_01356}.
FT   METAL        69     69       Iron-sulfur (4Fe-4S). {ECO:0000255|HAMAP-
FT                                Rule:MF_01356}.
FT   METAL       134    134       Iron-sulfur (4Fe-4S). {ECO:0000255|HAMAP-
FT                                Rule:MF_01356}.
FT   METAL       163    163       Iron-sulfur (4Fe-4S). {ECO:0000255|HAMAP-
FT                                Rule:MF_01356}.
SQ   SEQUENCE   225 AA;  25611 MW;  41BA61A5DE98BBCC CRC64;
     MDYTLTRIDP NGENDRYPLQ TQETVSGDPL EQHVHRSVYM GKLENAMHDM VNWGRKNSLW
     PYNFGLSCCY VEMVTSFTAV HDVARFGAEV LRASPRQADF MVVAGTCFTK MAPVIQRLYE
     QMLEPKWVIS MGACANSGGM YDIYSVVQGV DKFLPVDVYI PGCPPRPEAY MQALLLLQES
     IGKERRPLSW VVGDQGVYRA NMQPERERKH AERIAVTNLR TPDEI
//
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