ID Q7D468_CLOAB Unreviewed; 316 AA.
AC Q7D468;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Fructokinase {ECO:0000313|EMBL:AAK78404.1};
GN OrderedLocusNames=CA_C0424 {ECO:0000313|EMBL:AAK78404.1};
OS Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS / VKM B-1787).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK78404.1, ECO:0000313|Proteomes:UP000000814};
RN [1] {ECO:0000313|EMBL:AAK78404.1, ECO:0000313|Proteomes:UP000000814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC {ECO:0000313|Proteomes:UP000000814};
RX PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA Smith D.R.;
RT "Genome sequence and comparative analysis of the solvent-producing
RT bacterium Clostridium acetobutylicum.";
RL J. Bacteriol. 183:4823-4838(2001).
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU003704}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE001437; AAK78404.1; -; Genomic_DNA.
DR PIR; A96952; A96952.
DR RefSeq; NP_347064.1; NC_003030.1.
DR RefSeq; WP_010963746.1; NC_003030.1.
DR AlphaFoldDB; Q7D468; -.
DR STRING; 272562.CA_C0424; -.
DR GeneID; 44996934; -.
DR KEGG; cac:CA_C0424; -.
DR PATRIC; fig|272562.8.peg.621; -.
DR eggNOG; COG0524; Bacteria.
DR HOGENOM; CLU_027634_6_1_9; -.
DR OrthoDB; 9813569at2; -.
DR Proteomes; UP000000814; Chromosome.
DR GO; GO:0008865; F:fructokinase activity; IEA:UniProt.
DR GO; GO:0006000; P:fructose metabolic process; IEA:UniProt.
DR CDD; cd01167; bac_FRK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43085:SF54; PUTATIVE-RELATED; 1.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00583; PFKB_KINASES_1; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU003704};
KW Reference proteome {ECO:0000313|Proteomes:UP000000814};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003704}.
FT DOMAIN 1..309
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 316 AA; 34358 MW; 60FD94967DA46586 CRC64;
MNNVLCIGEL LIDFICSDID TTLSKGENFK KKAGGAPANV TAAISKLGGS ASFLGKVGND
PFGHFLKETL DEVKVDTSML IMDNNSSTTL AFVSLQANGE RDFVFNRGAD GLLRYDEINL
DKVYSNKIIH FGSATALLGG EMTDTYLKIM EEAKKRGIII SFDPNYRDNL WENRTEEFIA
ISRKCIELAD FVKLSDEELK IISGEKNIKN GVKLLASNNK VIAVTLGKEG TMISNGEEVE
IIESIKIKSI DSTGAGDAFV GAFLYKLSEA LEARDILSDF NKIKENVRFA NKVGAIVCTK
LGAISSLPSL SEVEGD
//
