ID   Q7KJC1_DROME            Unreviewed;       566 AA.
AC   Q7KJC1;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   24-JAN-2024, entry version 89.
DE   SubName: Full=L(2)01289 long form {ECO:0000313|EMBL:AAF34748.1};
DE   Flags: Fragment;
GN   Name=hlk {ECO:0000313|FlyBase:FBgn0010482};
GN   Synonyms=l(2)01289 {ECO:0000313|FlyBase:FBgn0010482};
GN   ORFNames=CG9432 {ECO:0000313|FlyBase:FBgn0010482};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:AAF34748.1};
RN   [1] {ECO:0000313|EMBL:AAF34748.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Manning G., Micklem D.R., Krasnow M.A.;
RT   "Sequence of l(2)01289 genomic locus.";
RL   Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AF216974; AAF34748.1; -; mRNA.
DR   AlphaFoldDB; Q7KJC1; -.
DR   PeptideAtlas; Q7KJC1; -.
DR   EnsemblMetazoa; FBtr0086137; FBpp0085470; FBgn0010482.
DR   AGR; FB:FBgn0010482; -.
DR   FlyBase; FBgn0010482; hlk.
DR   VEuPathDB; VectorBase:FBgn0010482; -.
DR   HOGENOM; CLU_001030_1_0_1; -.
DR   ChiTaRS; l(2)01289; fly.
DR   Bgee; FBgn0010482; Expressed in crop (Drosophila) and 19 other cell types or tissues.
DR   ExpressionAtlas; Q7KJC1; baseline and differential.
DR   CDD; cd02961; PDI_a_family; 2.
DR   Gene3D; 3.40.50.11390; -; 2.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 3.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR19991; L 2 01289; 1.
DR   PANTHER; PTHR19991:SF3; LETHAL (2) 01289, ISOFORM F; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 4.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   2: Evidence at transcript level;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..566
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004287760"
FT   DOMAIN          38..170
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   NON_TER         566
FT                   /evidence="ECO:0000313|EMBL:AAF34748.1"
SQ   SEQUENCE   566 AA;  64505 MW;  B20316B5A57C40B0 CRC64;
     MTFTRLKTLS LLVCALLALS FPGHVSGAGN NNNKKGSQPV APPEPEAVIE EVNAKQLEKL
     LADKDYVAVF WYARSCVTCD KVLAELEKID DDTDSFGVDF VKINDKRLAK QYGIKNFPAL
     TYFREKEPII YDGDLMDEEG VLDFLTSLEA MDLPDRIEEV NAKILQKIIE DTDFVAVLFC
     PDHETCPPRV MDKQQCRKCA KALQELENID DEADQLGIGF VKIHDEALAD EYNLGNLPAL
     VYYRHQTPII YEGELQREED VLEWLVQNKS TGDEDDVIED VTSKTLSTLI SNIDNLVVLF
     YDHGNDDSMT VLEELEQIDD DCDKHGIQFV KIDDAKAAAD YGIDSIPAIV YFEKEIPNVY
     DGDLMDEEQI LKWLLGQLER DEIEDVTDEM LDTMIKEGRV IAVLFYDNND KKSQKVLEEL
     ENIDDECDAL GITFVKIDNP EEAVEYGINK VPKLIYFEKG IPTIYEGNLE DEEKLLKWLT
     DQTSSDQIED ITDEMLDLII EKMPHVAVLF YDKDQKKSQK ILAELENIDD ECDQNDIAFV
     KIDDDKEAKE WGIDEIPSIV LFERGI
//