ID Q7KJP4_PLAVI Unreviewed; 597 AA.
AC Q7KJP4;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Merozoite surface protein 1 {ECO:0000256|ARBA:ARBA00022062};
DE AltName: Full=Merozoite surface antigen {ECO:0000256|ARBA:ARBA00031689};
DE AltName: Full=PMMSA {ECO:0000256|ARBA:ARBA00032276};
DE Flags: Fragment;
OS Plasmodium vivax (malaria parasite P. vivax).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5855 {ECO:0000313|EMBL:AAF91166.1};
RN [1] {ECO:0000313|EMBL:AAF91166.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C103 {ECO:0000313|EMBL:AAF91166.1};
RX PubMed=10960170; DOI=10.1016/S0166-6851(00)00238-3;
RA Putaporntip C., Jongwutiwes S., Seethamchai S., Kanbara H., Tanabe K.;
RT "Intragenic recombination in the 3' portion of the merozoite surface
RT protein 1 gene of Plasmodium vivax.";
RL Mol. Biochem. Parasitol. 109:111-119(2000).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC {ECO:0000256|ARBA:ARBA00004589}.
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DR EMBL; AF199403; AAF91166.1; -; Genomic_DNA.
DR AlphaFoldDB; Q7KJP4; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR010901; MSP1_C.
DR InterPro; IPR024730; MSP1_EGF_1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF12946; EGF_MSP1_1; 1.
DR Pfam; PF07462; MSP1_C; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Merozoite {ECO:0000313|EMBL:AAF91166.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 568..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..422
FT /note="Merozoite surface 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07462"
FT DOMAIN 492..528
FT /note="Merozoite surface protein EGF"
FT /evidence="ECO:0000259|Pfam:PF12946"
FT DOMAIN 535..574
FT /note="EGF"
FT /evidence="ECO:0000259|Pfam:PF12947"
FT REGION 131..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAF91166.1"
SQ SEQUENCE 597 AA; 66291 MW; D87EBEE42D213467 CRC64;
YYKARAKYYI GEPFPLKTLS EESLQKEDNY LNLEKFRVLS RLEGRLGKNI ELEKENISYL
SSGLLHVLTE LKEIINDKKY SGKDHAKNIA EVKKALQAYQ ELIPKVTSQE STSVAVTVPG
AVVPGVPTAA AAGSGASGAV PPAGGPSPPA TGGVVPGVVE SAEAQTKAQA QDYAEDYDKV
IALPLFGNND DDGEEDQVTT GEAESEAPEI LVPAGISDYD VVYLKPLAGM YKTIKKQLEN
HVNAFNTNIT DMLDSRLKKR NYFLEVLNSD LNPFKYSSSG EYIIKDPYKL LDLEKKKKLI
GSYKYIGASI DKDLATANDG VTYYNKMGEL YKTHLDGVKT EIKKVEADIK AEDDKIEKIG
SDSTKTTEKT QSMAKKAELE KYLPFLNSLQ KEYESLVSKV NTYTDNLKKV ISNCQLEKKE
AEITVKKLQD YNKMDEKLEE YKKSEKKNEV KSSGLLEKLM KSKLIKENES KEILSQLLNV
QTQLLTMSSE HTCIDTNVPD NAACYRYLDG TEEWRCLLTF KEEGGKCVPA SNVTCKDNNG
GCAPEAECKM TDSNKIVCKC TKEGSEPLFE GVFCSSSSFL SLSFLLLMLL FLLCMEL
//
