ID   Q7MCU0_VIBVY            Unreviewed;      1505 AA.
AC   Q7MCU0;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2003, sequence version 1.
DT   27-MAR-2024, entry version 130.
DE   SubName: Full=Non-ribosomal peptide synthetase module {ECO:0000313|EMBL:BAC97322.1};
GN   OrderedLocusNames=VVA1297 {ECO:0000313|EMBL:BAC97322.1};
OS   Vibrio vulnificus (strain YJ016).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=196600 {ECO:0000313|EMBL:BAC97322.1, ECO:0000313|Proteomes:UP000002675};
RN   [1] {ECO:0000313|EMBL:BAC97322.1, ECO:0000313|Proteomes:UP000002675}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJ016 {ECO:0000313|EMBL:BAC97322.1,
RC   ECO:0000313|Proteomes:UP000002675};
RX   PubMed=14656965; DOI=10.1101/gr.1295503;
RA   Chen C.Y., Wu K.M., Chang Y.C., Chang C.H., Tsai H.C., Liao T.L., Liu Y.M.,
RA   Chen H.J., Shen A.B., Li J.C., Su T.L., Shao C.P., Lee C.T., Hor L.I.,
RA   Tsai S.F.;
RT   "Comparative genome analysis of Vibrio vulnificus, a marine pathogen.";
RL   Genome Res. 13:2577-2587(2003).
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DR   EMBL; BA000038; BAC97322.1; -; Genomic_DNA.
DR   STRING; 672.VV93_v1c42170; -.
DR   KEGG; vvy:VVA1297; -.
DR   eggNOG; COG1020; Bacteria.
DR   HOGENOM; CLU_000022_2_1_6; -.
DR   Proteomes; UP000002675; Chromosome II.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd19535; Cyc_NRPS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   PANTHER; PTHR45527:SF10; PHENYLOXAZOLINE SYNTHASE MBTB; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00668; Condensation; 2.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
FT   DOMAIN          24..458
FT                   /note="Condensation"
FT                   /evidence="ECO:0000259|Pfam:PF00668"
FT   DOMAIN          500..885
FT                   /note="Condensation"
FT                   /evidence="ECO:0000259|Pfam:PF00668"
FT   DOMAIN          927..1266
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   1505 AA;  167707 MW;  819D20D4461CAC3B CRC64;
     MCADRRQTDR RSDGLCLDFN MKEMTAMQAA YWLGRQKGSA MEGLAAHLYA EFDGRDLNRE
     ALSMAVRALY AKHPMLRLAI TAEGQQHILP LSACHQLTVE DIARYSKPEA EQFLHNKRER
     MSHQILDLNQ SSPIDISVTL LANNEHRLHI DADMIACDAQ SFRIVVEDLA RLYLSAQESD
     LAMSEEPQIT YFHYLDHQQA DRYLAQRKAS DKQWWQARLS SLPPEPPLPY LSHQDNEARP
     QTQRLAHQFT HQERVALEAL AKEHHLTLTQ LFLALFSQVI ATGAREHRFR LNVPTFHRGI
     YDPQIEQAVG DFSNLLIFSA HVDKTQTLLS HCRQVANQLN LLLSHETYSG VQVMRDLSRL
     AGQVQRSPVV FTSGMDIDGG ELFSQQVTDS LGRMNWVISQ GAQVTLDAQI APAYGGILAN
     WDIRSDLLEQ EVIESMFAHY VALIRRLATF PQIMHQTLEQ LDAALGQSES ENISATPLSN
     LQKSYLLGRS TQIALGGVAM HEFREYRGNL ATETVRENLT RLVEQLPALR THIDQEKLLQ
     FVSPIIELNL KTFDFQHLSR EKALLAVEPL REHYRHKMHD LSCSPWEVCV VQLPPEYASR
     TNTIIFTSFD ALIVDGRSHS IILATLLGQQ EDGIQGLLAP RSPKRQGPVI DTAKRAQDER
     YWQEKLHRDC LPPALPWKQP LETIRTSRYA RESLQISHAE LQQLTLLGAE NGLFVNSLLT
     AAIVQVLACW TTENGMRIGF PVVIPQQDEL AGNESTFVIL EHEKSDASVL RQALDLQSDM
     LEALEHLDFS GVDVNRLLMN GSSPALALPV VITNGLSWQT LKETDDVALF SGVTQTPQMA
     LDIRLTYDEQ KNLIVSFDYA VDALETNVVC DILNALKTLL QQLSESQQGL LPSSSFLDLS
     HYRLNSDETQ RDPSDFLSHI ARQLFDETNE KTAIICGETT VSYAELGSKV ACVMGQLNAR
     GLQQGSVVAI CLPRSVEHLV MTLACSLSGM VWVPIDASSP YDRLAYLLSN CNAELVVTQH
     GDVVASVAFS ELLSPIASEA PLPSYEQLSR LSQSTQTAYY LYTSGTTGKP KCVVVNNQAT
     SNVIGQTCRE WSISSQDVIM SVTPYHHDMS VFDVFAAFSS GATLVLPGAD GEKDALKWNQ
     LIEKHKVTIW VSVPAILEML LSCTQGSQLQ SLRLVAQGGD YIKPATIAQL RALESSIRLI
     SLGGPTETTI WSIWHELTDA DVSTIPYGRP LPGNRYFILD ERQQHVPQGV VGRIYTVGVN
     LAQGYLENGE LKQTDFVTIN DDRGEPVRAF RTGDQGYYRQ DGNIIFSSRV NGYVKVRGVR
     VSLPDIEKEL LKHPLIANAV VVDYLDGNGD SALAALFTLN SDKPLTAQQL RQFAQQCLPQ
     SHIPTHFMPM TVLPLSANGK VDRKQCQARV AASLLPSESG THAEREKGEV LNPTLLAQIE
     QIYREVIATD EIFDDAQELA FLSRGLLPSH LVSIASLLNQ RFASQLSASQ LVRCQSAQQV
     AALLA
//