ID Q7MU81_PORGI Unreviewed; 368 AA.
AC Q7MU81;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Efflux transporter, MFP component, RND family {ECO:0000313|EMBL:AAQ66685.1};
GN OrderedLocusNames=PG_1666 {ECO:0000313|EMBL:AAQ66685.1};
OS Porphyromonas gingivalis (strain ATCC BAA-308 / W83).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=242619 {ECO:0000313|EMBL:AAQ66685.1, ECO:0000313|Proteomes:UP000000588};
RN [1] {ECO:0000313|EMBL:AAQ66685.1, ECO:0000313|Proteomes:UP000000588}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-308 / W83 {ECO:0000313|Proteomes:UP000000588};
RX PubMed=12949112; DOI=10.1128/JB.185.18.5591-5601.2003;
RA Nelson K., Fleishmann R., DeBoy R., Paulsen I., Fouts D., Eisen J.,
RA Daugherty S., Dodson R., Durkin A., Gwinn M., Haft D., Kolonay J.,
RA Nelson W., White O., Mason T., Tallon L., Gray J., Granger D., Tettelin H.,
RA Dong H., Galvin J., Duncan M., Dewhirst F., Fraser C.;
RT "Complete genome sequence of the oral pathogenic bacterium Porphyromonas
RT gingivalis strain W83.";
RL J. Bacteriol. 185:5591-5601(2003).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; AE015924; AAQ66685.1; -; Genomic_DNA.
DR RefSeq; WP_005875127.1; NC_002950.2.
DR AlphaFoldDB; Q7MU81; -.
DR STRING; 242619.PG_1666; -.
DR EnsemblBacteria; AAQ66685; AAQ66685; PG_1666.
DR KEGG; pgi:PG_1666; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_1_10; -.
DR Proteomes; UP000000588; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000588};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..261
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 368 AA; 40199 MW; 4BFC19D2698EF220 CRC64;
MKKYFKIFLW VLLAVAVIGT FMFLWQKSKA KPKEYQIETV TKQDTIESKT VITGTVEPRD
EVLIKPQMNG IVAELLHEAG DVVQSGDVIA RLTVVPEMIQ LSQAESRVRM AEISYEQGKE
SYARSKDLFD KSVIALEEFE AAEANFAKIK EELSNAREAM EIVKKGASSR TAKQSNTLVR
STVTGKILNV PVKVGNSVIQ ANTFNEGTTI ASIADMNDLI FVGKIDETEV GRIRLGSPMR
ISVGALGKES FPATVEYLAP KGSIVNGAVL FEVKASVHIP SDRVIRAGYS ANAEIVLEGA
YGVPAIPEAC IEFSGDSTFV QVVKAEKPLQ TERRQVKTGV SNGSNIEIKS GLKVGEKVRG
IEKTEEKK
//
