ID Q7N5N5_PHOLL Unreviewed; 100 AA.
AC Q7N5N5;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE RecName: Full=Negative regulator of flagellin synthesis {ECO:0000256|ARBA:ARBA00017823};
DE AltName: Full=Anti-sigma-28 factor {ECO:0000256|ARBA:ARBA00030117};
GN Name=flgM {ECO:0000313|EMBL:CAE14206.1};
GN OrderedLocusNames=plu1913 {ECO:0000313|EMBL:CAE14206.1};
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01) (Photorhabdus luminescens subsp. laumondii).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265 {ECO:0000313|EMBL:CAE14206.1, ECO:0000313|Proteomes:UP000002514};
RN [1] {ECO:0000313|Proteomes:UP000002514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01
RC {ECO:0000313|Proteomes:UP000002514};
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- FUNCTION: Responsible for the coupling of flagellin expression to
CC flagellar assembly by preventing expression of the flagellin genes when
CC a component of the middle class of proteins is defective. It negatively
CC regulates flagellar genes by inhibiting the activity of FliA by
CC directly binding to FliA. {ECO:0000256|ARBA:ARBA00024739}.
CC -!- SIMILARITY: Belongs to the FlgM family.
CC {ECO:0000256|ARBA:ARBA00005322}.
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DR EMBL; BX571865; CAE14206.1; -; Genomic_DNA.
DR RefSeq; WP_011146175.1; NC_005126.1.
DR AlphaFoldDB; Q7N5N5; -.
DR STRING; 243265.plu1913; -.
DR GeneID; 24166729; -.
DR KEGG; plu:plu1913; -.
DR eggNOG; COG2747; Bacteria.
DR HOGENOM; CLU_149304_2_2_6; -.
DR OrthoDB; 7062942at2; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR035890; Anti-sigma-28_factor_FlgM_sf.
DR InterPro; IPR007412; FlgM.
DR InterPro; IPR031316; FlgM_C.
DR NCBIfam; TIGR03824; FlgM_jcvi; 1.
DR Pfam; PF04316; FlgM; 1.
DR SUPFAM; SSF101498; Anti-sigma factor FlgM; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|ARBA:ARBA00022795};
KW Cell projection {ECO:0000313|EMBL:CAE14206.1};
KW Cilium {ECO:0000313|EMBL:CAE14206.1};
KW Flagellum {ECO:0000313|EMBL:CAE14206.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002514};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 38..89
FT /note="Anti-sigma-28 factor FlgM C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04316"
SQ SEQUENCE 100 AA; 10862 MW; ED699CF26F0F775B CRC64;
MSIERTHPLL AIAAVQQRPT NESAQGTRKT AGVTLQSSDA QVKLSEAQTK LVQPSSQDIN
IQKVQKLKEA IAQGSLKMNS GKIADALLKE AAENFQYDKK
//
