ID Q7N726_PHOLL Unreviewed; 4070 AA.
AC Q7N726;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE SubName: Full=Photorhabdus luminescens subsp. laumondii TTO1 complete genome segment 5/17 {ECO:0000313|EMBL:CAE13637.1};
GN OrderedLocusNames=plu1344 {ECO:0000313|EMBL:CAE13637.1};
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01) (Photorhabdus luminescens subsp. laumondii).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265 {ECO:0000313|EMBL:CAE13637.1, ECO:0000313|Proteomes:UP000002514};
RN [1] {ECO:0000313|Proteomes:UP000002514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01
RC {ECO:0000313|Proteomes:UP000002514};
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBCELLULAR LOCATION: Host cytoplasm, host cytosol
CC {ECO:0000256|ARBA:ARBA00023586}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; BX571863; CAE13637.1; -; Genomic_DNA.
DR RefSeq; WP_011145661.1; NC_005126.1.
DR STRING; 243265.plu1344; -.
DR GeneID; 24167302; -.
DR KEGG; plu:plu1344; -.
DR eggNOG; COG1073; Bacteria.
DR eggNOG; COG2931; Bacteria.
DR eggNOG; COG3064; Bacteria.
DR eggNOG; COG3210; Bacteria.
DR HOGENOM; CLU_000137_1_0_6; -.
DR OrthoDB; 9798884at2; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0044164; C:host cell cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd20501; C80_RtxA-like; 1.
DR CDD; cd21073; toxin_BteA-MLD_like; 1.
DR Gene3D; 2.160.20.160; -; 1.
DR Gene3D; 3.40.50.11050; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR020974; CPD_dom.
DR InterPro; IPR038383; CPD_dom_sf.
DR InterPro; IPR049824; RtxA-like_C80.
DR InterPro; IPR048568; RtxA_C.
DR InterPro; IPR011509; RtxA_toxin.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR NCBIfam; NF012221; MARTX_Nterm; 1.
DR PANTHER; PTHR12277; ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12277:SF205; ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF11713; Peptidase_C80; 1.
DR Pfam; PF07634; RtxA; 41.
DR Pfam; PF21735; RtxA_C; 7.
DR PRINTS; PR00313; CABNDNGRPT.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF51120; beta-Roll; 1.
DR PROSITE; PS51771; CGT_MARTX_CPD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Host cell membrane {ECO:0000256|ARBA:ARBA00022511};
KW Host cytoplasm {ECO:0000256|ARBA:ARBA00023200};
KW Host membrane {ECO:0000256|ARBA:ARBA00022511};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000002514};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Toxin {ECO:0000256|ARBA:ARBA00022656};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 2990..3170
FT /note="Peptidase C80"
FT /evidence="ECO:0000259|PROSITE:PS51771"
FT REGION 1878..1897
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1947..1987
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2677..2699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3616..3642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1738..1772
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 4070 AA; 438780 MW; 7D744F724B3426B3 CRC64;
MGKSSNRSTE YFFTGKYYDD NDGNSIIAIG IGGEVYAYGG DDDVTIGSFK VDVYHTNGEL
SVKGASGYTG ISKTGNGGLS FSGAAGTAFI DHTGETGDLS YSGAAGYNKL VRKGSSGDTR
FKGAGGYNQL WHETDQGNVY FAGAGAANKI DRTWSNYYEG TQGDVTFNGA GAANSIDSRI
ESGDITLNGV GADNHIVRKG REGNIILHGA GAANRIERTR HSEDQYGQTQ GDITLEGAGG
YNKLYSDVAH GNIHFTGAGA YNEITRAGAR NEIEFAQAKD IVMTSATMEE RGIQQSQQVK
AVKSEVEPDT YLFAIADNVN TKVVAVRLQN NPDTGKLRYY ATSWYKEGNH LKDIAKENID
VNNGFISVKG DDAITLANIN VVYRQETIVQ GVEEVLLTDK WVNYSDGTNI KAKNVTLGSA
KMGGYAISSN GLKIDVSPVK SNQQPDTYVY AIFLEPYTKV VEVKLANDDE TGKLKYIARS
WYKKGDHTGR LANERFSYPR GYQSIGAGYT LSQLHYDLNV TDEITDCLTD IEGYSEQDVI
KSSKNGGDSS GNIYFIGAGG GNIITSNVTH GNINFTGAGA ANIILHSSTF GNTYFEGGGG
ANVIVKNGEE GDLSFRGAGL ANVLVHQSQR GKMDVYAGGA VNVLVRVGDG RYLAHLLSYG
NISIHKGNGD SRVLMLGGYN THTQIGDGSA NWFGAGGFNV ITQAGTGDIF SVFLGGANVL
TKLGAGDMVA GMLGGANIIT HLSDETETTN TTAIALGGAN IFTKKGKGHT QAVMGGGANV
LTHIGDGNTT GVMLGGANIL TKVGKGDMTG IMFGVGNVLT HVGDGLTLGV MAAAGNIFTK
VGEGTSIAAM IGAGNLFTHV GKGDAWALMG GVGNIFTKVG DGDALALMVA AGNVFTHIGD
GTSVALMLAK GNIATKVGNG MTLAAMIGKA NIFTHVGEGN TFAAMIGGAN VLTKVGNDLT
AALMVGKANI YSHVGNGTSI GLFAGELNVM TKVGNGTTLA AMFGKANMMT HVGDGLTGVL
ALGEANIVTK VGDDFMGVVA AAKANVITHV GDATTAAILF GKGNILTKVG DGTTVGLLIS
DVGNVMTHVG EGTTVGFAKG KANLITKIGD GAGVNAAWGE ANILTQVGNG DRYNFAKGKA
NLMTKVGKGQ EVTVVQGDAN IITHVGNGDD YTGAWGKANV ITKIGDGRNV VLAKGKANIV
TQVGQGDSFN ALWSEGNIVT KVGDGMQVTV AKGKANVTTT VGNGLNVTAA HGDANINTHV
GNGVSVNLAW GKHNINTKVG NGLNVAVMKG QANANIHVGD GLGINASYAR NNVAVKIGNG
DFYSFSVTNS NKLSSLFEHI KQTTLGVGGS QAINYLVHGE EANTSGTHKG RGAINLAEVS
GIDGFQMDEI APISSDLNHS FNGAITAVET PDVSSIEGAL SQKTLSVSDQ DENLIVNGDF
EQGELGWQST HGIEAYNPAS DYGLDNTGDG ERVSKFDVDK NTVIWQELQN LSEGEVVSLT
FDFMSHFERV DRDLSGSGIM VLWNGKSVFS TSGPRAIWRT QKLDLMAKAG TNRIEFKGTG
QDDGFSYILD NIIVKSETSL IVNNDLEQGK LDWQSTNDIA AYSSVSTDGP NNTRYGERVS
ELDVDKNTTI YQDLQNRSEG EVISLSFDFA NRPDAYSVDN GMDVFWNDKL VFSTFGDAAK
WQNKTLELTA KAGSNRIEFK GTGLSDGVGY ILDNVIAKSK SSQQANIITE HVKQDKAAQN
ALSDKEKAEK DRRLLEQEKE KQLAEIAKSQ SQLELTDQAA VSQNGLTQRN AIEAEAQAET
DKLVSMTQGL DALGDYANYS GQSGDQWRNQ FASQFLDHAQ DKLNDIKFIA QRKLMHARQA
ITDNQQHVKE AVKKSEVGVA QSEQHHASAK QDIAAAQKKA ELRKEEALLQ QQRAEKAEND
ANIAYQGAEY RGKRDIAAAE NKIAQVQEDV RGAKQSDSKP DRTGAGGSGL SGNGYESTGA
GETGSYIDPE LIPEAEKKFY KGLTEEELQA LDDAKQAVDR LQINASIRVE NTGVLTTSKF
AKGQSDDRVI PTSNSSGERV RRVPRISGIN LKSLGNDVKV EQKNSAIFEN AKFNLLKEGN
KLFINPNVRT LGRKRKLSTA LATVRDTFYK TMSHFDEEHI LLLERAIADW QQHSPKEFAL
RTNQVNLVRF KMGRMIEHLQ AQRAESAGVL GIAVAPQHAE HLTQRVIFDG TGRVVGLKGG
ITQNEINRLI EWQITPLTRT NSTAEREAPK TESESLIAFM SRLETANIPE ARFLIGRARG
LWLTGQVTSK ETIKLFDDAA SQLQAYPELH GLVLSLQADA HREKSTTQYI DNLFGRRFDS
EVAHTLVKMA SPDALATSRR IGQFLVQEFE LYMQSTADSP VLDGQIDIRM QAFAEKIKKD
IRPWFSRVPE LTAFLQKPTL DNFKIMMTKV DNGFEMIKIP FLAVKMSNTD GMGLHLSQWK
AEADIFYREE IYKARSTSSK LTNMADVTYK VKLTEQQTND YGIALPYQPS GDQYGDFLYG
RKVAAGRVLT PGQETTLERN ALAQGHSVVT GASGSTNIMV HLNNYIASQD PTFSQEQAYL
NTLAFLVFDG GHSVNESLVV YKALQMTGDE RRQVLQNYTA SYMDLMDIAG DKGKLSINQA
LNNAFEKTQH LYRENTPERE QNDSPVEALQ ALSGKNGASE SVLIENDDTP PRDKDSLNPV
TRFFNNELYG FKEDRRHISD KTQTILNDAV ANGKSSKITL KGEEGRLTGY YHQGDIKPDD
ISTAAEKKVV LFLHGSGLSA EEQAHDIQSH YQKQGIDILA VNMRGYGGSD GSPGEQGFYQ
DARTMFRYLV QDRGIKPGNI ILHGYSVGGP VAADLARYAS QNNQAVSGLL LDRPISSMTK
TITAHDVPNP GGMIGALAKA MNGQFSVEKN LKGLPINTPI MLLTDNQGLG HEGEKLRARL
AASGYRVSGE QTFYGHVESG ALMSQYTDRI VSTLSDFQNK NRDGVKNSWQ KSDNRGTRFD
GQIIIQMEND PIVAKAALNL ASKHRKSSVV VKLDSNGKYH VIYGDPAGLS GKLRWQIVGH
GRNESAQNNT RLSGYSADEL AIKLKQFSQN FEQAGKPDRI SIVGCSLISD DKRNGFAYRF
ITALDKQGIR SEVSARRSEV AVDATGRKFT RDKNHQWVNK LDDNKLVLRW NEQDELTTTT
EKLRRGVAES DINLAKVGHT EADSATRGAI ADNHDVFTAP GKRKNRVELG SNPQSEPLGY
AGNIQVNVGD GEFTAINWGT SNVGIKVGTG GFKSLAFGDN NVMVHIGEGD SKHSVNLAGY
QALEGAQMFI GNRNVSFNQG RSNDLIVMMD KSIPTPPLVN PFDGAARITG VLKSIAHSGE
ERNWLAAQNQ QWTLSGAKKF VRDMSGLDQT SSVDYKTLVD LDSQLKRSSR GLKSDTEAAL
NKKYHQWLNG HGNNIDTKKM SRVDKFRQAN EKLAFNFAVG GQGADIQVTT GSWNFMFGDH
IQSILDTNLG SLFGLMTQQY STTGLAKTTF TYNLQDLPRQ LKNKLLGRLA GVNAETTLAD
IFGVDYTPEG QIVARTGEPV DGKAILREML EVIKQFGGDQ LSVFTDPDKL IEGLKQNANM
SADGIESFFV SHGLKEKAPD ENREKSVPDA VNSGKSQADD KSERALGFNS LNLPNLFATI
FSKDKQQEMK SLVTNLKENL TADLLNMEQK TFDFLRNSGH LQGDSDIHIS LGNYNFNWGG
DGKDLGAYLG DNNNFWGGRG DDVYYSIGTS NIFTGGEGDD LGVLMGRENW MFGGSGDDTA
VVAGRINHVF MGEGNDQTFV FGEGGVIDAG NGRDYVVTSG NYNQVDTGED QDYAVTIGNN
NRVELGEGND FGRVFGNDNR IDGNMGNDVI KLMGYHAVIN GGEGDDHLIA ATISKFSQFD
GGEGQDLLVL GGYQNHFQGG AGVDSFVVSG KVIDSQVDDI NAEDMIAFND IDWQDLWFQR
SGYDLVLSVN RPTQDKTAQG LFESVGSVTF RDYFNGNRAK LVTQMGRKDA SGEREFTALS
DNAVDTLIQA MSSFAPTAGD NGFIEALDNR EKMAITTAWA DTTIGKGKFA
//
