ID Q7PTG9_ANOGA Unreviewed; 1330 AA.
AC Q7PTG9;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 5.
DT 27-MAR-2024, entry version 134.
DE SubName: Full=AGAP007611-PA {ECO:0000313|EMBL:EAA03938.6};
GN ORFNames=AgaP_AGAP007611 {ECO:0000313|EMBL:EAA03938.6};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA03938.6};
RN [1] {ECO:0000313|EMBL:EAA03938.6}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03938.6};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA03938.6}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03938.6};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA03938.6}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03938.6};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA03938.6}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03938.6};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA03938.6}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03938.6};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAA03938.6}.
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DR EMBL; AAAB01008807; EAA03938.6; -; Genomic_DNA.
DR RefSeq; XP_308260.5; XM_308260.5.
DR STRING; 7165.Q7PTG9; -.
DR PaxDb; 7165-AGAP007611-PA; -.
DR GeneID; 1269617; -.
DR KEGG; aga:AgaP_AGAP007611; -.
DR VEuPathDB; VectorBase:AGAP007611; -.
DR eggNOG; KOG4293; Eukaryota.
DR HOGENOM; CLU_269388_0_0_1; -.
DR OMA; VKDFYQP; -.
DR OrthoDB; 5361809at2759; -.
DR PhylomeDB; Q7PTG9; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd09631; DOMON_DOH; 2.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR045266; DOH_DOMON.
DR InterPro; IPR005018; DOMON_domain.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000082; SEA_dom.
DR PANTHER; PTHR46901; GH04942P; 1.
DR PANTHER; PTHR46901:SF2; GH04942P; 1.
DR Pfam; PF03351; DOMON; 2.
DR SMART; SM00664; DoH; 2.
DR PROSITE; PS50836; DOMON; 2.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS50024; SEA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..1330
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014587905"
FT TRANSMEM 1084..1107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..238
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 540..665
FT /note="DOMON"
FT /evidence="ECO:0000259|PROSITE:PS50836"
FT DOMAIN 774..893
FT /note="DOMON"
FT /evidence="ECO:0000259|PROSITE:PS50836"
FT DOMAIN 939..1066
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT REGION 313..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1136..1317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1153..1177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1226..1253
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1265..1310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 228..237
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1330 AA; 146817 MW; 5F465236EADE3DCE CRC64;
MARSVGPGPG LPGAARLMVL LCLLPLLPRP DPAEAHVALT FPPARKYDLD FLDNSRTKPP
CGMPKGSLKT SFIEGSTFNV SWHLAYPHRG GFRLEILDTK EKPILSLTPS SKERRFVRED
ATAQQFQVSL PRNFTCRDCT LRLVRQADEW GGNYRFWSCA DVDIVPRREH HETCSGHGKF
IARCKCDKKY YGPRCEFWDE CVTNQDCGIQ GTCVDLGGTS LPRRQCYCRL GWFGPGCNKK
SPIKSTDIDY SVYKAKTLSP DLNVYWRVLK EQKELEVVLK VNGTSWVALG VRPRKLTAEC
KNFPLIAAPG AAGSEAGVAE PEPASEPTSE PGKEGNQKTL QSQSELIEIV LSLFSEEPNS
EPEPGAEPGA EPGAEPGAEP GAEPEPGAEP GAEPGVMIIK TLYSLLFSSV VEPKSEPEPA
SEPGAEPNAE PEPKSESEPG AEPTSEPASE PASEPSSEPG KKIEHEDFRT TISNSMVGII
LEPKSEPEPE PGAEPGAEPG AEPEPKSEPE PTSEPEPESA TEPTPEPKGP AKKSKRAAAT
TPAAEPEPAS EPAAKPKPKP TAAAAGPKLK LNPYTPRHDF NPMDCTDIVI GTARGDNHRV
WDYYTRDRST PRMDSFWGGK SDLTATGGFE RDGVTTIVYR RPLAASEPTD HEIVDDLMHV
IWARGQEPGA YVHSPPSGVE KETASVREFY QPDELKYHGH RMQRGVTQIN FLEEEVQHKV
AVAATNADGV TATPDGASGQ GVIVPAGPVG HELDNECHGF YKYPRTCDPE QANCEYFLSW
QTVARGEAVH FHLETKHTAT WTGVGFSDDQ RMSQTDAIIG WVDKSGRPFL MDTWINGYSA
PKLDDRQDLY NASGAIQNGR TVLDFTRKRV TGDESDLAFA EDRCLYMMFP IEGGAFNPVN
KKLGKHASVP VVTDTRVCIK SCAKQFEQLL TVAATPAPDR IAYGASIKLT NLAAGFQVPD
SGTPEHRDLS KSVTDTFNGV LREVPGFYRT DVQEFEKYVD ADGSVVVKMN ILVDKEMKNG
TKNLLADDPA KLELTLHNLM VNNLSSGKVG AFSVDPTYLE FTQLEGQASS PKEEYELLPA
GVRLYLILGC IAGLVFIAIV QATCTIIKTR RTNRLKDQLI PNSAWKDYSS NTNYAFDNFE
PESKHHKGRS SDRGYSNGNS QQTTLQMSHS PNKSQYYEID RTDGGGMPTH RNGSSGYPYP
PGQPRHGYDR TGDRSSYADR AYSLPRPMHQ QQQQQQMQQR HHQEMQSRPT GDYYTQDRRG
KSRNNGSHYA GNGHQPQHQS SQQHHHQQQQ QHQQQQRPMP DSSDLYFTPT QRKYSGEVVR
VFVDYNKDKK
//
