ID Q7Q553_ANOGA Unreviewed; 753 AA.
AC Q7Q553;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 4.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=AGAP006632-PA {ECO:0000313|EMBL:EAA10920.4};
GN ORFNames=AgaP_AGAP006632 {ECO:0000313|EMBL:EAA10920.4};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA10920.4};
RN [1] {ECO:0000313|EMBL:EAA10920.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10920.4};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA10920.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10920.4};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA10920.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10920.4};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA10920.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10920.4};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA10920.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10920.4};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MAD1 family.
CC {ECO:0000256|ARBA:ARBA00008029}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAA10920.4}.
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DR EMBL; AAAB01008960; EAA10920.4; -; Genomic_DNA.
DR RefSeq; XP_316663.4; XM_316663.4.
DR AlphaFoldDB; Q7Q553; -.
DR STRING; 7165.Q7Q553; -.
DR PaxDb; 7165-AGAP006632-PA; -.
DR GeneID; 1277219; -.
DR KEGG; aga:AgaP_AGAP006632; -.
DR VEuPathDB; VectorBase:AGAP006632; -.
DR eggNOG; KOG4593; Eukaryota.
DR HOGENOM; CLU_393441_0_0_1; -.
DR InParanoid; Q7Q553; -.
DR OMA; RDFYKQM; -.
DR OrthoDB; 8224at2759; -.
DR PhylomeDB; Q7Q553; -.
DR GO; GO:0000776; C:kinetochore; IBA:GO_Central.
DR GO; GO:0072686; C:mitotic spindle; IBA:GO_Central.
DR GO; GO:0005635; C:nuclear envelope; IBA:GO_Central.
DR GO; GO:0051315; P:attachment of mitotic spindle microtubules to kinetochore; IBA:GO_Central.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IBA:GO_Central.
DR Gene3D; 3.30.457.60; -; 1.
DR Gene3D; 6.10.250.90; -; 1.
DR InterPro; IPR008672; Mad1.
DR PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR Pfam; PF05557; MAD; 1.
DR SUPFAM; SSF75704; Mitotic arrest deficient-like 1, Mad1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT COILED 92..119
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 152..356
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 397..424
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 466..553
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 586..657
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 753 AA; 86696 MW; C78FB614F232D3AC CRC64;
MDGEGCDETL TTYGMSSSTA IGSSRLSFEN SASFELSRKK RRISGPGCDR TTDTMYEGNV
SGDSFSTTAT GYNTTTQVAQ SPWESRRIKA DLIEARSRIT FLKKEIEHLN TEMATTQLRN
QHKISSLEKE LGFSGQKVTD LEKHLQLVRK REHVAKQDLN KVRTQLQQLK TEADGRQFEL
RQALQRLEQK YDSDTGELNT EIRDLTTQVN DLEQQLTLAQ DELDTTREIN DTLQSKADAY
DQTKRELEAT QDRLAEAESR VKTLEYEVGS YEDWKSLSKV SADRLANTTE IEKENVRLKD
QLKNLQSLIG DKLLLEEQVA SSQARLKDLE QKDALSAALE VRVKELEREL VEWRQLGKDY
TPKESLVSAK TMRNRIEQIL QKDLVLANEQ SSVQTEKHQI QGRIEELQSE NALLNGRLAD
YKRAQEGLQS IVHRAQKKLN LVTGERDYLK QLLESYENDL TISHSVVGSE ADKKQLRARI
EMLEKTLTGY KDLCQKQEAD LQANKVLPDI SFVLTSEQYE KLRKEIDELR LENERLKRRK
DELEVEVENR TLRAQINRPC PTQTTKLVRY INSPATEDIV AEHNTKLKLM AEIERLKLHI
QRLQETNQDL TECLHNTDET GNMTMKIKES VDLRMQLKEL QAKYDQRKEL YQQSSEDFRT
VVNLLFGFKI DRISGSYFQL RSQYAESPDE YLNFALAPDG SVLTLLESDY AASLRDLVET
QFKTHNSVPV FLSSLTLELF NRTTMTVQYC NAE
//
