ID Q7QDA0_ANOGA Unreviewed; 720 AA.
AC Q7QDA0;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 5.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=AGAP003019-PA {ECO:0000313|EMBL:EAA07937.5};
GN Name=1272933 {ECO:0000313|EnsemblMetazoa:AGAP003019-PA};
GN ORFNames=AgaP_AGAP003019 {ECO:0000313|EMBL:EAA07937.5};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA07937.5};
RN [1] {ECO:0000313|EMBL:EAA07937.5, ECO:0000313|Proteomes:UP000007062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA07937.5,
RC ECO:0000313|Proteomes:UP000007062};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA07937.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA07937.5};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA07937.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA07937.5};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA07937.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA07937.5};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA07937.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA07937.5};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EnsemblMetazoa:AGAP003019-PA}
RP IDENTIFICATION.
RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP003019-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AAAB01008859; EAA07937.5; -; Genomic_DNA.
DR RefSeq; XP_311858.5; XM_311858.5.
DR AlphaFoldDB; Q7QDA0; -.
DR STRING; 7165.Q7QDA0; -.
DR PaxDb; 7165-AGAP003019-PA; -.
DR EnsemblMetazoa; AGAP003019-RA; AGAP003019-PA; AGAP003019.
DR GeneID; 1272933; -.
DR KEGG; aga:AgaP_AGAP003019; -.
DR VEuPathDB; VectorBase:AGAP003019; -.
DR eggNOG; KOG1914; Eukaryota.
DR HOGENOM; CLU_007630_3_1_1; -.
DR InParanoid; Q7QDA0; -.
DR OMA; CFRGPFV; -.
DR OrthoDB; 23291at2759; -.
DR Proteomes; UP000007062; Chromosome 2R.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR GO; GO:0031123; P:RNA 3'-end processing; IBA:GO_Central.
DR Gene3D; 1.25.40.1040; -; 1.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045243; Rna14-like.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR19980:SF0; CLEAVAGE STIMULATION FACTOR SUBUNIT 3; 1.
DR PANTHER; PTHR19980; RNA CLEAVAGE STIMULATION FACTOR; 1.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 10.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007062}.
FT DOMAIN 377..647
FT /note="Suppressor of forked"
FT /evidence="ECO:0000259|Pfam:PF05843"
FT REGION 682..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 720 AA; 82793 MW; F8DBF35698795E9A CRC64;
MTQQLKDQLK FDIEWGHERL VRAQQTVEVR PFDVESWSLL VREGQSRHVN EVRSLYESLV
CVFPTTARYW KVYIEQEMKY RNYERVEKLF QRCLVKILNI DLWKLYLTYV KETKAGLSTH
KEKMAQAYDF ALEKIGMDLH SFSIWTDYIM FLKSVDAVGS YAENQKITAV RKVYQRAVIT
PIIGIEHLWK DYIAFEQNIN PIISEKMSVE RSRDYMNARR VAKELEIVTK GLNRNLPAVP
PTVTKEEIKQ VELWKKYIAF EKSNPLRSED NALVTRRVMF AIEQCLLVLT HHPAVWHQAA
QYLDQSSKLL VEKGDLNAAK VFSDEAANIL ERAINSVLSR NALLYFAYAD FEEGRLKYDK
VHQMYNKFLA INDIDPTLAY IQYMKFARRA EGIKSARAVF KKAREDVRST YHVFVAAALM
EYYCSKDKDI AFRIFELGLK RFGGSPEYVM CYIDYLSHLN EDNNTRVLFE RVLSSGGLTP
QLSVEVWNRF LEFESNIGDL SSIVKVERRR SAVLEKLKEF EGKETAQLVD RYKFLDLYPC
SPSELKSIGY SETRGMLSVT GVKPPPAPVP EQPEQPQQLA RPDFSQMIPY KPKPNAFPGE
HPVPGGTFPQ PAALAALCAI LPPPVSFQGP FVSVDKIIEV FNRIQLPEVP PPPSDSTADS
RLFELAKSVH WIVDDSTYAS EGGLKRRRMA PGGEDSDDEA VAPAPPANDI YRLRQQKRFK
//
