ID Q7S1S1_NEUCR Unreviewed; 465 AA.
AC Q7S1S1;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 24-JAN-2024, entry version 115.
DE SubName: Full=Transcription initiation factor TFIID complex 60 kDa subunit {ECO:0000313|EMBL:EAA29314.1};
GN ORFNames=NCU07757 {ECO:0000313|EMBL:EAA29314.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA29314.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA29314.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF6 family.
CC {ECO:0000256|ARBA:ARBA00007688}.
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DR EMBL; CM002240; EAA29314.1; -; Genomic_DNA.
DR RefSeq; XP_958550.1; XM_953457.2.
DR AlphaFoldDB; Q7S1S1; -.
DR STRING; 367110.Q7S1S1; -.
DR PaxDb; 5141-EFNCRP00000007954; -.
DR EnsemblFungi; EAA29314; EAA29314; NCU07757.
DR GeneID; 3874688; -.
DR KEGG; ncr:NCU07757; -.
DR VEuPathDB; FungiDB:NCU07757; -.
DR HOGENOM; CLU_021711_3_0_1; -.
DR InParanoid; Q7S1S1; -.
DR OMA; YFVQFIA; -.
DR OrthoDB; 1529at2759; -.
DR Proteomes; UP000001805; Chromosome 2, Linkage Group V.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:0000124; C:SAGA complex; IEA:EnsemblFungi.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:EnsemblFungi.
DR GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IEA:EnsemblFungi.
DR GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:EnsemblFungi.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0061629; F:RNA polymerase II-specific DNA-binding transcription factor binding; IEA:EnsemblFungi.
DR GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR GO; GO:0006325; P:chromatin organization; IEA:EnsemblFungi.
DR GO; GO:2000144; P:positive regulation of DNA-templated transcription initiation; IEA:EnsemblFungi.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:EnsemblFungi.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR CDD; cd08050; TAF6C; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037796; TAF6.
DR InterPro; IPR011442; TAF6_C.
DR InterPro; IPR046344; TAF6_C_sf.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR PANTHER; PTHR10221:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR Pfam; PF02969; TAF; 1.
DR Pfam; PF07571; TAF6_C; 1.
DR SMART; SM00803; TAF; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..71
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|SMART:SM00803"
SQ SEQUENCE 465 AA; 51013 MW; 16EC1B2A5E55ECD4 CRC64;
MAGEGPKLLW NPENVKDVAE SIGINLTEEP LRVLTQDVEY RIGQVVVEAL RFMRAANRTT
LTVQDVSQAL RVLDVEPLYG YDSTRPLRYG EASIGPGQPL FYIEDEEVDF EKVINAPLPK
VPRDMSFTAH WLAIDGVQPS IPQNPTTAET SSKDLLPKGP GANPAVAALA GNDNVAFRPA
VKHVISKELI LYFDKVQAAI MDDDPDEEKT RLRSAALDSV RSDPGLHQLV PYFVSFINNQ
VTHRLDDLFV LRQMMELTGA ILDNPSIFLD PYASSLAAPV LTCLMARKLG GSESSLEGTD
ALKDQYRLRE VAASLLGTIA RKYSKTNALL RPKLTRTCLK FFLDPSKSPA VLYGAISGLA
AAGGPEAVRI LVLPNLKMFD EGILTPLREK GEASHFEYEA LVGGIMKAIE TLVEGITLPV
VADVAELERE GQLVIEFLGR TIGERVARLG NQHLNRGILE VRHLE
//
