ID Q7S3Y7_NEUCR Unreviewed; 686 AA.
AC Q7S3Y7;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 3.
DT 24-JAN-2024, entry version 91.
DE RecName: Full=Protein SQS1 {ECO:0000256|ARBA:ARBA00018964};
GN ORFNames=NCU02434 {ECO:0000313|EMBL:EAA30203.3};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA30203.3, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA30203.3, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the SQS1 family.
CC {ECO:0000256|ARBA:ARBA00010306}.
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DR EMBL; CM002242; EAA30203.3; -; Genomic_DNA.
DR RefSeq; XP_959439.3; XM_954346.3.
DR AlphaFoldDB; Q7S3Y7; -.
DR STRING; 367110.Q7S3Y7; -.
DR PaxDb; 5141-EFNCRP00000003163; -.
DR EnsemblFungi; EAA30203; EAA30203; NCU02434.
DR GeneID; 3875586; -.
DR KEGG; ncr:NCU02434; -.
DR VEuPathDB; FungiDB:NCU02434; -.
DR HOGENOM; CLU_007254_0_0_1; -.
DR InParanoid; Q7S3Y7; -.
DR OrthoDB; 1333919at2759; -.
DR Proteomes; UP000001805; Chromosome 7, Linkage Group VII.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR CDD; cd02646; R3H_G-patch; 1.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR034082; R3H_G-patch.
DR PANTHER; PTHR14195; G PATCH DOMAIN CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR14195:SF2; GH10944P; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF01424; R3H; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS51061; R3H; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001805}.
FT DOMAIN 508..570
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT DOMAIN 643..686
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 75309 MW; C650882E3003E93F CRC64;
MAPKKGKRPH AGPKTARMRA TTAQKTIRSV ATAESLNTGI AASNHGFTMR DEARNTTSHQ
LLLGTSLRTK PVHFVSAGYI EPLKQPELLP PASPTLVGMD TAEEIQLQLS EIQEATVEAV
GEKSKPLGID VQKSEPSRND STHDEIDPVA KTDGNVEATE QLFFFDVARD ETVVGTDQPP
VPIPNRQPLA DHSDSSEEII LFRGRTTHVQ PTVQPVCEPR NHATNMTRQP MVGSTGTAAA
STSTKVVIAA RPTSAQGGRP TSAFKRKSPK RDSKRDSKRA QKYMEDDDED EILADYIANL
ADDSDGDDIL TSHLRTFANR RDLGGNENSI NFGDESDDMD AMSETGGSNA SDDSDENEQL
DIDEEDIDDE TLARLFAKQE ELGMGSNELV LFSEEAAFNV QKAKNKKRAS RTEGFPSATA
VADAFDGLEL SDGWVNPGFI PPGRNRRNKQ PPNFNVSDSG IELVLKTAWQ KDRERKKQRK
LEREELRAQG LLGKRANPDD LRVKYLTGMT LDDIKTELVA FLLTTEESLQ FPPMDKQARK
VLHELANKFK IKSQSTGKGD QRRPILYRTK ATLRYKGHRS EEVVTHVDQA AVRINRKYFH
RLDAKGKPSY KTPSGGGGGR SGHQAVSVRE GEIVGASAPE LGQENKGRAM LEKMGWSKGM
GLGSLDNKGI LEPVKQVVKR SKAGLG
//
