ID Q7S689_NEUCR Unreviewed; 479 AA.
AC Q7S689;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=S-adenosyl-L-methionine-dependent methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=NCU04764 {ECO:0000313|EMBL:EAA31061.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA31061.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA31061.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM002241; EAA31061.1; -; Genomic_DNA.
DR RefSeq; XP_960297.1; XM_955204.3.
DR AlphaFoldDB; Q7S689; -.
DR STRING; 367110.Q7S689; -.
DR PaxDb; 5141-EFNCRP00000004491; -.
DR EnsemblFungi; EAA31061; EAA31061; NCU04764.
DR GeneID; 3876444; -.
DR KEGG; ncr:NCU04764; -.
DR VEuPathDB; FungiDB:NCU04764; -.
DR HOGENOM; CLU_037990_3_1_1; -.
DR InParanoid; Q7S689; -.
DR OMA; GTTWLIE; -.
DR OrthoDB; 35684at2759; -.
DR Proteomes; UP000001805; Chromosome 5, Linkage Group VI.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42912; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR42912:SF60; METHYLTRANSFERASE OMS1, MITOCHONDRIAL; 1.
DR Pfam; PF13489; Methyltransf_23; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 98..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 39..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..85
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 52987 MW; 3400690960EFFF90 CRC64;
MATRIPLSLR GASQRSSHIF LTANRLTLAS RAFTTTSLLA KSKKLPPQPS KASKLSRPST
TAQPIPEVTP EPQSEEPPKS NSNAQDLGTL LQQRRWPLLF SGLTALIMGA YISMLIASLS
RGPDACSHVD PATGQLPVTG RPRELDSLTS NPVVNDRILR EKAMAFDNGL NMPERVMGIR
LLRKWLGTRV KGHVLEVAVG TGRNLQFYDW TEVVKGPVTG RELTAEEEKE EEEKAKERIR
SVLDQGGKDE EKKRDKDWVE KMKMPGALEG EMLTFTGVDI SEGMMGVARQ RLRENVPGGK
QLVPKGAFLT SREASESRIG EGKRGEGQEV LLSTLEDRIR LVRADAEAKL PEAPAYPARV
GSKEEGKYDT VVQTFGLCSV SNPLALLQNM AGVVKPDTGR IILLEHGKGW SDWINEKLDA
WAPQHFSRYG CWWNRDIEKL VKEAEQKVPG LEIVKIERPG FFQAGTTVLV QLKVKSQGK
//
