ID Q7SDF4_NEUCR Unreviewed; 652 AA.
AC Q7SDF4;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 122.
DE RecName: Full=mRNA export factor mex67 {ECO:0008006|Google:ProtNLM};
GN ORFNames=NCU09317 {ECO:0000313|EMBL:EAA34785.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA34785.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA34785.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- SIMILARITY: Belongs to the NXF family. {ECO:0000256|ARBA:ARBA00009285}.
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DR EMBL; CM002236; EAA34785.1; -; Genomic_DNA.
DR RefSeq; XP_964021.1; XM_958928.2.
DR AlphaFoldDB; Q7SDF4; -.
DR SMR; Q7SDF4; -.
DR STRING; 367110.Q7SDF4; -.
DR PaxDb; 5141-EFNCRP00000009135; -.
DR EnsemblFungi; EAA34785; EAA34785; NCU09317.
DR GeneID; 3880170; -.
DR KEGG; ncr:NCU09317; -.
DR VEuPathDB; FungiDB:NCU09317; -.
DR HOGENOM; CLU_024991_1_0_1; -.
DR InParanoid; Q7SDF4; -.
DR OMA; YGGHEAW; -.
DR OrthoDB; 10284at2759; -.
DR Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IBA:GO_Central.
DR CDD; cd14342; UBA_TAP-C; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR040736; Mex67_RRM.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR InterPro; IPR030217; NXF_fam.
DR InterPro; IPR005637; TAP_C_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR10662; NUCLEAR RNA EXPORT FACTOR; 1.
DR PANTHER; PTHR10662:SF22; NUCLEAR RNA EXPORT FACTOR 1; 1.
DR Pfam; PF18444; RRM_9; 1.
DR Pfam; PF03943; TAP_C; 1.
DR SMART; SM00804; TAP_C; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50177; NTF2_DOMAIN; 1.
DR PROSITE; PS51281; TAP_C; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 388..558
FT /note="NTF2"
FT /evidence="ECO:0000259|PROSITE:PS50177"
FT DOMAIN 597..651
FT /note="TAP-C"
FT /evidence="ECO:0000259|PROSITE:PS51281"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 652 AA; 70990 MW; 8A47353D1CAD22BD CRC64;
MAPPTGPRAG TGRAPPRGPR ATGGGGGIQK RRANPRTDRD GDVSMDAPAG GSGRGGLASG
GRGRGSKDAR GGRGAVNSRT ASRVVQNLQN YVSGGPVGKT QSNMATLKIH GMSNSKATGN
RDGGLRSLLT FLERKASKDK AVTIGKSIMD GDYVWITVRK DDAPEILRLN GFTYAGAPLT
ITETTERMPR PEDKISKAAE ETKQKLTAVL AARYNPELKL LDLSSLGTDP ILSSMGTFDS
KDRAEKAFKV LVVIASQQYK TAAEKREGIQ AISLASNGLN DVMQVFTLAT SLPDIKRLDL
SSNNLDSLSK ISKWQHRFQY LEELHLTGNP ITTQPDFVAE LIKWFPSLQN INGQIVRSPQ
EVTEALKGMH PTPLPQFPSN LRDGEANVAS IFVQVFFPMF DSDRARLAAE FYDDDSWFSI
QAIANSGRNL PWKTYLKYSR NVHKLGEKNP ATVQRLFTGG NLIADMWKAL PSTRHPSMEN
PGAWLIDCHT FPNLADPTGH GFATGLLITV NGQFEESDTT ENLYGKRTFT RTFILGPSKP
SNPPPVHPYR VISDQLTLHD WTPAETPAGQ APVANQVPQV PVTNAVPPAE PVMLDDATKN
QLIQEVMKRT GMTAEYSELC LSGTANWNFE LALKSFEEQR ANLPPTAFIN AV
//
